中国组织工程研究2016，Vol.20Issue(20)：3032-3040,9.DOI:10.3969/j.issn.2095-4344.2016.20.019
关节镜下保留残端重建前交叉韧带与不保留残端重建的Meta分析
Preserving-remnantversusremoving-remnant for arthroscopic anterior cruciate ligament reconstruction：aMeta-analysis
摘要
Abstract
BACKGROUND:There are controversies about preserving the remnant in the anterior cruciate ligament reconstruction procedure because of its uncertain therapeutic effects. <br> OBJECTIVE:Tocompare the efficacy and safety of preserving-remnant with removing-remnant for arthroscopic anterior cruciate ligament reconstruction using a meta-analysis. <br> METHODS:A computer-based online search was conducted in PubMed,Embase,the Cochrane Library, CDSR, CBM, and CNKI databases by using the English key wordsof “anterior cruciate ligamentAND remnant (OR stump)ANDrandomized controled trial (RCT)ORquasi-RCT” and the Chinese key words of“anterior cruciate ligament reconstruction, preserving-remnant, removing-remnant” to screen the relevant articles publishedfrom 1995 to July 2015. Meta-analysis was performed using Review Manager 5.3 software. <br> RESULTS AND CONCLUSION:A total of 13 randomized controled trials were included. The meta-analysis resultsshowed that there were no statisticaly significant differences in KT1000/2000 scores (OR=-0.28, 95%CI:-0.76-0.20,P=0.25), the good rate of synoveal coverage (OR=-0.30, 95%CI:-0.30-0.90,P=0.32), and the incidence of cyclops leions (OR=0.87,95%CI: 0.63-2.90,P=0.44). Postoperative Lysholm scores (OR=2.45, 95%CI: 0.52-4.39,P=0.01), proprioceptive function (OR=-1.72, 95%CI:-3.32 to 0.13,P=0.03), tunnel enlargement (OR=-0.66, 95%CI:-1.08 to-0.23,P=0.002) in preserving-remnant were superior to removing-remnant for arthroscopic anterior cruciate ligament reconstruction. These results suggest that both preserving-remnantandremoving-remnant for arthroscopic anterior cruciate ligament reconstructioncanobtain satisfactory antero-posterior stability of the knee. Preserving-remnant exhibits superiority in post-operative scores of the knee, proprioceptive function, tunnel enlargement.Furtherhigh-quality randomized controled trials are warranted because of some low-quality studies and the existing biases.关键词
组织构建/组织工程/肌肉肌腱韧带/前交叉韧带/保留残端/不保留残端/重建/随机对照/本体感觉/Cyclops病变/骨道扩大/膝关节稳定性/Meta分析分类
医药卫生引用本文复制引用
张磊,谢崇新,白靖平..关节镜下保留残端重建前交叉韧带与不保留残端重建的Meta分析[J].中国组织工程研究,2016,20(20):3032-3040,9.基金项目
新疆生产建设兵团自然科学基金(2015AD004)Funding:the Natural Science Foundation of Xinjiang Production and Construction Corps, China, No.2015AD004 （2015AD004）
