中国组织工程研究2016，Vol.20Issue(22)：3212-3218,7.DOI:10.3969/j.issn.2095-4344.2016.22.003
膝骨关节炎全膝关节置换前骨质疏松的相关因素分析
Osteoporosis-related factors in patients with knee osteoarthritis before total knee arthroplasty
任志帅 1张学利 2程招军 1孙和军 1孙振辉 1崔子健 1张黎龙 1林雍智 1张仁赞 1彭兵1
作者信息
- 1. 天津市人民医院，天津市 300000
- 2. 南开大学医学院，天津市 300017
- 折叠
摘要
Abstract
BACKGROUND:The greatest risk of osteoporosis in total knee arthroplastyisperioperative and long-term periprosthetic fractures. However, limited by the traditional concept of osteoarthritis patientswhousualy not associated with osteoporosis, domestic clinical trials have not given enough attention to the osteoporosis before total knee arthroplasty. <br> OBJECTIVE:To analyze the osteoporosis and its relative factors in osteoarthritis patients before total knee arthroplasty. <br> METHODS:Data of 81 cases (81 knees) of knee osteoarthritiswhounderwenttotal knee arthroplasty in the Department of Joint Surgery of Tianjin People’s Hospital from January 2012 to November 2014 were retrospectively analyzed. They received lumbar spine and hip bone mineral density examination before surgery. The correlation of bone mineral density with age, body mass index, knee motion range,and knee deformity was analyzed before surgery. The independent risk factors for osteoporosis before replacement were analyzed. <br> RESULTS AND CONCLUSION:(1) Of 81 patients, there were normal bone mineral density in 25 cases (31%), osteopenia in 35 cases (43%),andosteoporosis in 21 cases (26%). Al 10 males had no osteoporosis and 21 in 71 female cases suffered osteoporosis (30%). Theincidence of osteoporosis in females was significantly higher than in male patients (P=0.046). (2) There was a linear correlation of bone mineral density with age and body mass index (correlation coefficientr=-0.230, 0.225). (3) The age of≥65 years and body mass index≥25 kg/m2were independent risk factors of osteoporosis before replacement (P< 0.05). (4) Patients with knee osteoarthritis had higher incidence of osteopenia and osteoporosis before total knee arthroplasty. The degree of osteoporosis was negatively correlated with age, but positively correlated with body mass index. The age of≥65 years and body mass index < 25 kg/m2were independent risk factors for preoperative osteoporosis. Thus, bone mineral density examination is essential for those patients before total knee arthroplasty.关键词
骨科植入物/人工假体/全膝关节置换/膝骨关节炎/骨密度/骨质疏松Key words
Subject headings:Arthroplasty, Replacement, Knee/Osteoarthritis/Bone Density/Osteoporosis/Tissue Engineering分类
医药卫生引用本文复制引用
任志帅,张学利,程招军,孙和军,孙振辉,崔子健,张黎龙,林雍智,张仁赞,彭兵..膝骨关节炎全膝关节置换前骨质疏松的相关因素分析[J].中国组织工程研究,2016,20(22):3212-3218,7.
