中国医疗设备2016，Vol.31Issue(5)：19-22,29,5.DOI:10.3969/j.issn.1674-1633.2016.05.005
一种实现术中实时在体组织良恶性鉴别检测的创新医疗设备系统
A Novel Medical Equipment System for Intraoperative Real-time in Vivo Discrimination of Tumor Tissues
摘要
Abstract
A novel medical equipment system aiming at real-time discrimination of tumor tissues in vivo during the process of tumor surgery is introduced in the paper. The physical principle of this system is based on the open-ended coaxial probe method for the measurement of the dielectric properties of tissues. The physical principle, structure of hardware, and design of software of the whole system are presented. Using the proposed system, the dielectric properties of targeted tissues can be obtained and the discrimination diagnosis can be fulfilled based on the fact that the dielectric properties of malignant tissues usually dramatically change compared with those of benign tissues. The precision of the system is proved to be high via blind measurement of liquids with the known dielectric properties. The prototype of the novel medical equipment has been built and applied at clinic measuring near 200 cases of stomach cancer, colorectal cancer, and breast cancer. The discrimination results are highly in accordance with the pathological reports, indicating that the novel medical system is promising for the application of real-time discrimination diagnosis of malignant tissues in vivo.关键词
介电特性/开端同轴探头法/组织良恶性鉴别检测Key words
dielectric properties/open-ended coaxial probe/discrimination diagnosis of malignant human tissues分类
医药卫生引用本文复制引用
辛学刚,厉周,蓝茂英,严晨,万旺,刘晓兰,邓官华,段松..一种实现术中实时在体组织良恶性鉴别检测的创新医疗设备系统[J].中国医疗设备,2016,31(5):19-22,29,5.基金项目
国家自然科学基金（61172034，61528102）；广东省自然科学基金（2015A030313234）；广东省省级科技计划项目（2015B020214006）；广州市科技计划项目（2014J4100160）部分资助；上海科技计划项目（15441907500）。 （）
