中国感染控制杂志2016，Vol.15Issue(5)：304-308,5.DOI:10.3969/j.issn.1671-9638.2016.05.004
神经外科患者手术部位感染及危险因素
Surgical site infection and risk factors of neurosurgical patients
摘要
Abstract
Objective To investigate the incidence and risk factors of surgical site infection(SSI)in neurosurgical patients in a tertiary first-class hospital,and provide reference for the prevention and control of SSI.Methods 47 neurological patients with SSI (49 patients developed SSI,2 were excluded from study due to the lack of appropriate control subject)from December 31 ,2011 to December 31 ,2012 were as infected group,and 94 patients without SSI (1 ∶2 matching)were as non-infected group,risk factors for SSI were analyzed retrospectively.Results There was no significant difference in general condition of two groups of patients (all P >0.05 );among 3 708 patients,49 (1 .32%)developed SSI;intracranial infection was the main type of SSI (89.80%);27 patients were performed ce-rebrospinal fluid (CSF)bacteriological detection,6 (22.22%)of whom were positive for CSF bacteriological detec-tion.Univariate conditional logistic regression analysis showed that risk factors for SSI in neurosurgical patients were operational risk assessment score (OR =2.04),frequency of preoperative antimicrobial use(OR =3.15 ),fre-quency of intraoperative antimicrobial use(OR=2.58),duration of operation(OR=2.70),surgical blood loss(OR=1 .72),indwelling drainage tube(OR=4.30),duration of indwelling drainage tube after operation(OR=2.06),and time for initial dressing change(OR=1 .66);Multivariate conditional logistic regression analysis showed that the in-dependent risk factors for SSI were frequency of preoperative antimicrobial use(P =0.03,OR =4.86),duration of operation(P =0.05,OR = 2.89 ),and time for initial dressing change after operation (P = 0.01 ,OR = 1 .92 ). Conclusion Risk factors for SSI in department of neurosurgery are multiple,duration of operation,duration of in-dwelling drainage tube after operation,and time for initial dressing change after operation are major risk factors.关键词
神经外科/手术部位感染/危险因素/配比病例对照/医院感染Key words
department of neurosurgery/surgical site infection/risk factor/case-control study/healthcare-asso-ciated infection分类
医药卫生引用本文复制引用
付菊芳,杨志芳,程瑶,张瑞娜,刘冰,史皆然,张永琴,戴丽文..神经外科患者手术部位感染及危险因素[J].中国感染控制杂志,2016,15(5):304-308,5.基金项目
陕西省自然科学基金项目（2014JM2－8149）；中华医院感染控制研究基金 （）
