中国感染控制杂志2016，Vol.15Issue(5)：317-320,4.DOI:10.3969/j.issn.1671-9638.2016.05.007
中药排痰液防治呼吸机相关性肺炎的临床研究
Effect of traditional Chinese medicine sputum discharge liquid on preventing and treating ventilator-associated pneumonia
摘要
Abstract
Objective To evaluate the effect of traditional Chinese medicine sputum discharge liquid on preventing ventilator-associated pneumonia(VAP).Methods A randomized double-blind,placebo-controlled study was con-ducted,according to the inclusion and exclusion criteria,patients with respiratory failure and mechanical ventilation in the intensive care unit (ICU)of a hospital in 2011 -2014 were selected and divided into treatment group and con-trol group.Treatment group received sputum discharge liquid in addition to conventional treatment,control group adopted simulation agent based on conventional treatment.The incidence,treatment effectiveness,occurrence time, and prognosis of VAP between two groups of patients were compared.Results A total of 139 patients were monitored,70 cases in treatment group and 69 in control group.The incidence of VAP in treatment group and con-trol group were 37.14% (n =26)and 57.97%(n =40)respectively;the average onset time of VAP in treatment group and control group were (76±3.2)hours and (45±8.9)hours after admission to ICU respectively;treatment effectiveness rates in treatment and control group were 88.46% and 55.00% respectively;the incidence,occurrence time,and treatment effectiveness rates of VAP between two groups of patients were both significantly different (all P <0.05).There were no significant difference in blood routine,liver and kidney function,urine routine,stool rou-tine,and electrocardiogram results between two groups of patients (all P >0.05 ).Conclusion Intervention in patients with mechanical ventilation by sputum discharge liquid can reduce the incidence of VAP,and has a positive effect on the prognosis of disease and pulmonary infection in patients.关键词
排痰液/呼吸机相关性肺炎/疗效/中医药Key words
sputum discharge liquid/ventilator-associated pneumonia/treatment effectiveness/traditional Chi-nese medicine分类
医药卫生引用本文复制引用
丁志红,左明晏,卓道勤,吕春兰..中药排痰液防治呼吸机相关性肺炎的临床研究[J].中国感染控制杂志,2016,15(5):317-320,4.基金项目
湖北省襄阳市科技局研究开发重点项目 （）
