中国药房2016，Vol.27Issue(15)：2035-2036,2037,3.DOI:10.6039/j.issn.1001-0408.2016.15.06
麦芪降糖丸联合胰岛素对妊娠期糖尿病患者相关指标的影响
Effects of Maiqi Jiangtang Pill Combined with Insulin on Related Indicators in Maternal Gestational Diabetes
摘要
Abstract
OBJECTIVE:To investigate the effects of Maiqi jiangtang pill combined with insulin on related indicators in mater-nal gestational diabetes. METHODS:135 GDM women were randomly divided into control group (69 cases) and observation group(66 cases). Control group was given diet controlling and exercise therapy,Novolin R insulin biosynthesis and protamine syn-thetic human insulin were injected before meals and bedtime from 4-6 units with the ratio of 4∶2∶3∶1,and decided whether to ad-just the insulin dose based on the blood glucose monitoring results(increase or decrease 2-4 units each times);observation group was additionally given 6 g Maiqi jiangtang pill,4 times a day. The treatment course for both groups was 15 d. Fasting plasma glu-cose(FPG),2 h postprandial glucose(2 h PG),glycated hemoglobin(HbA1c),body mass index(BMI),maternal pregnancy out-comes(preeclampsia,preterm labor,puerperal infection,postpartum hemorrhage,neonatal asphyxia,low-weight children and noc-turnal hypoglycemia)and incidence of adverse reactions in 2 groups were observed. RESULTS:FPG,2 h PG,HbA1c,BMI,pre-eclampsia,preterm labor,low-weight children,neonatal asphyxia and nocturnal hypoglycemia in observation group were signifi-cantly lower than control group,the differences were statistically significant(P<0.05);there were no significant differences in the puerperal infection and postpartum hemorrhage between 2 groups (P>0.05). And there were obvious adverse reactions between 2 groups during treatment. CONCLUSIONS:Maiqi jiangtang pill combined with insulin can effectively reduce the blood glucose of GDM women,with good safety.关键词
麦芪降糖丸/胰岛素/妊娠期糖尿病/血糖/妊娠结局Key words
Maiqi jiangtang pill/Insulin/Gestational diabetes/Blood glucose/Maternal pregnancy outcomes分类
医药卫生引用本文复制引用
翟悦静,朱思宇,左学军,朱慧芳..麦芪降糖丸联合胰岛素对妊娠期糖尿病患者相关指标的影响[J].中国药房,2016,27(15):2035-2036,2037,3.基金项目
河北省科学技术研究与发展计划项目 （）
