中国医学创新2016，Vol.13Issue(15)：16-18,19,4.DOI:10.3969/j.issn.1674-4985.2016.15.005
3D打印导航模板膝关节置换术联合应用氨甲环酸的有效性和安全性研究
Efficacy and Safety of Combined Application of Tranexamic Acid and Three-dimentional-printed Navigation Template in the Total Knee Arthroplasty
谭成波 1柳椰 1马旭 1翟良全 1杜明昌 1杨政博 1付恂1
作者信息
- 1. 沈阳市骨科医院 辽宁 沈阳 110044
- 折叠
摘要
Abstract
Objective:To explore the efficacy and safety of combined application of Tranexamic Acid and three-dimentional-printed navigation template in reducing the blood loss of primary unilateral total knee arthroplasty.Method:A total of 60 patients who received primary unilateral total knee arthroplasty in Orthopedics Hospital of Shenyang City from December 2013 to November 2015,were divided into the experiment group(30 cases) and the control group(30 cases).Patients in the experiment group received three-dimentional-printed navigation template and Tranexamic Acid Injection with clamping the drainage tube for 3 hours,patients in the control group received the same volume of physiological saline injection and the drainage tube maintained open,the drainage tubes in all patients were removed 48 hours after surgery.Result:There were no significant differences in age,gender,left or right side,BMI,ASA score,PT,APTT,FIB,hemoglobin level and HCT before surgery between two groups(P>0.05).There were significant differences in hemoglobin level and HCT 1 day and 3 days after surgery between two groups(P<0.05).Duration of operation,postoperative total blood loss,postoperative suction drainage,the hidden blood loss and blood transfusion volume of patients in the experiment group were significantly less than those in the control group(P<0.05).Venous thrombosis was not found by deep vein colour duplex ultrasonography of both lower limbs 7 days after surgery.Conclusion:Combined application of three-dimentional-printed navigation template and intra-articular injection of Tranexamic Acid and clamping the drainage tube for 3 hours can reduce blood loss significantly after the primary unilateral total knee arthroplasty without increasing the occurrence of deep-vein thrombosis,the method is effective and safe.关键词
关节成形术/置换/膝关节/3D打印导航模板/氨甲环酸/失血Key words
Arthroplasty/Replacement/Knee joint/Three-dimentional-printed navigation template/Tranexamic Acid/Blood loss引用本文复制引用
谭成波,柳椰,马旭,翟良全,杜明昌,杨政博,付恂..3D打印导航模板膝关节置换术联合应用氨甲环酸的有效性和安全性研究[J].中国医学创新,2016,13(15):16-18,19,4.
