摘要
Abstract
ObjectiveTo investigate the clinical feasibility of autologous blood transfusion in cardiac surgery and explore its influence on systemic inflammatory reaction after surgery.MethodFrom January 2013 to January 2015 in our hospital 120 patients underwent selective cardiac surgery were divided into control group (57 cases) and observation group (63 cases). Observation group patients received autologous blood transfusion while control group patients received non- autologous blood transfusion. Recorded the amount of thoracic cavity drainage and banked blood transfusion volume. Then detected the levels of terminal compound (sC5b-6), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) of both groups.Result Observation group recollected packed red blood cells with a mean value of 937 ml and the dosage of banked blood in observation group was obviously less than control group (P<0.05). The levels of sC5b-6、IL-6, TNF-α were significant lower in observation group compared to control group at the same time point (P<0.05). 1 hour after operation, Hb, HCT and PLT were all lower than preoperative in the two groups (P<0.05), but 12, 24, 48 hours after operation, there were no significant differences in Hb, HCT, PLT between the two groups (P>0.05). At each time point after operation, there were no significant differences in pH, PaO2, SaO2, PT, TT, APTT, FIB levels between the two groups (P>0.05), and there was no significant difference between the two groups at the same time (P>0.05).ConclusionApplying autologous blood transfusion technique in cardiac surgery can alleviate the systemic inflammatory recations of patients after cardiopulmonary bypass and with the additional benefits of less transfusion volume of banked blood.关键词
自体血液回输/心脏手术/可行性/炎性反应Key words
Autologous blood transfusion/Cardiac surgery/Feasibility/Inflammatory reaction
