中国医学前沿杂志（电子版）2016，Vol.8Issue(4)：112-115,4.
血液透析联合血液灌流在急性重度有机磷农药中毒患者抢救中的应用价值
The application value of hemodialysis combined with hemoperfusion in the treatment of acute severe organophosphorus pesticide poisoning
何学鹏 1陈惠仁 1杨凯 1陈鹏 1刘兵 1张媛 1王芳 1郭智 1刘晓东 1楼金星1
作者信息
- 1. 北京军区总医院 血液科，北京 100700
- 折叠
摘要
Abstract
ObjectiveTo explore the clinical effect of hemodialysis combined with hemoperfusion in the treatment of acute severe organophosphorus pesticide poisoning.Method100 cases of acute severe organophosphorus pesticide poisoning patients admitted in our hospital from June 2011 to June 2015 were divided into combined group and conventional group according to the random number table method, 50 cases in each group. Conventional group patients were treated with gastric lavage and catharsis, cleaning skin, protecting gastric mucosa and other conventional treatment. In addition to the routine treatments, combined group patients were treated with hemodialysis combined with hemoperfusion. Compared the dosage of atropine, recovery time, hospitalization time, the incidence of multiple organ failure and cholinesterase activity of the two groups before and after treatment.ResultThe differences of cure rate and mortality rate between the two groups were significant (P<0.05). Combined group patients with atropine dosage were less than control group, the recovery time, hospitalization time weres shorter than control group, multiple organ failure rate were lower than conventional group (P<0.05). Two groups of patients before treatment of cholinesterase activity had no obvious difference (P>0.05), and the cholinesterase activity of combined group was significantly higher than conventional group after treatment (P<0.05).Conclusion Hemoperfusion combined with hemodialysis can effectively improve the prognosis of patients with severe acute organophosphorus pesticide poisoning, reduce the dosage of atropine, accelerate the recovery of the patients, avoid multiple organ failure, worthy of clinical application.关键词
有机磷农药中毒/血液透析/血液灌流Key words
Organic phosphorus pesticide poisoning/Hemodialysis/Hemoperfusion引用本文复制引用
何学鹏,陈惠仁,杨凯,陈鹏,刘兵,张媛,王芳,郭智,刘晓东,楼金星..血液透析联合血液灌流在急性重度有机磷农药中毒患者抢救中的应用价值[J].中国医学前沿杂志（电子版）,2016,8(4):112-115,4.
