中国医学前沿杂志（电子版）2016，Vol.8Issue(5)：61-64,4.
不同靶控输注全身麻醉诱导方案对重度子痫前期剖宫产产妇及新生儿的影响
Effects of different target controlled infusion of general anesthesia induction program on maternal and infant of severe preeclampsia
摘要
Abstract
ObjectiveTo investigate the effects of different target controlled infusion of general anesthesia induction program on maternal and neonatal effects of cesarean section in severe preeclampsia.Method 84 cases of severe preeclampsia maternal were selected as the research objects in our hospital from January 2011 to June 2014 intends to general anesthesia for cesarean delivery operation, according to the random number table method they were divided into A, B, C groups, 28 cases in each group, three groups of maternal were target controlled infusion of propofol and remifentanil. Maternal in group A were treated with target controlled infusion of propofol 5μg/ml, remifentanil 4 ng/ml; group Bmaternal with target controlled infusion of propofol 3.5μg/ml, remifentanil 4 ng/ml; maternal in group C had a target controlled infusion of propofol 3.5μg/ml, remifentanil 3.4 ng/ml; after two minutes of tracheal intubation and began the operation. Comparative observation immediately after three groups of maternal before anesthesian (T0), tracheal intubation (T1), skin incision (T2), postoperative extubation (T3), the SBP and DBP, mean arterial pressure (MAP), heart rate (HR), neonatal cesarean section and neonatal 1 minute, 5 minutes Apgar scores.ResultThere were no significant differences in SBP, DBP, HR, MAP among the three groups at T0, T1 and T2 times (P>0.05), at T3 time group B of maternal SBP, DBP, MAP, HR were significantly higher than the same time points of group A, C of maternal (P<0.05), there were no significant differences in the hemodynamic parameters of group A and group C at each time point (P>0.05). Neonatal umbilical cord blood pH of three groups of maternal,newborn cutting time had no significant differences (P>0.05), group B neonatal 1 minute Apgar score were less than group A and group C (P<0.05), neonatal 5 minutes Apgar score compared among the three groups had no significant differences (P>0.05).ConclusionSevere preeclampsia maternal line during cesarean delivery target controlled infusion induction dose of propofol 3.5μg/ml, fentanyl 4 ng/ml, to maternal hemodynamic interference may be less, has no obvious effect on neonatal.关键词
全身麻醉/重度子痫前期/靶控输注/剖宫产术Key words
General anesthesia/Preeclampsia/Target controlled infusion/Cesarean section引用本文复制引用
刘悦,白耀武..不同靶控输注全身麻醉诱导方案对重度子痫前期剖宫产产妇及新生儿的影响[J].中国医学前沿杂志（电子版）,2016,8(5):61-64,4.基金项目
唐山市科技局计划项目 （）
