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首页|期刊导航|中国药业|思连康改善抗生素相关性腹泻患儿菌群失调随机对照研究

思连康改善抗生素相关性腹泻患儿菌群失调随机对照研究

王妍妍 关晶 温韬雪

中国药业2016,Vol.25Issue(7):5-7,3.
中国药业2016,Vol.25Issue(7):5-7,3.

思连康改善抗生素相关性腹泻患儿菌群失调随机对照研究

Bifidobacterium Tetravaccine Tablets in Treating Dysbacteriosis of Children with Antibiotic Associated Diarrhea

王妍妍 1关晶 1温韬雪1

作者信息

  • 1. 哈尔滨医科大学附属第二医院,黑龙江 哈尔滨 150001
  • 折叠

摘要

Abstract

Objective To study effect and nursing of Bifidobacterium Tetravaccine Tablets to improve dysbacteriosis of children with an-tibiotic associated diarrhea. Methods 174 cases children with antibiotic associated diarrhea were divided into observation group and control group, 87 cases in each group. The control group was given conventional rehydration, gastrointestinal mucosa protectant treatment etc., and the observation group was added with Bifidobacterium Tetravaccine Tablets. All patients were given the ADD nursing. The dys-bacteriosis, anti-diarrhea effect, diamine oxidase, therapy effect were compared between two groups. Results The total effective rate of the observation group was 97. 70%, which was significantly higher than 86. 21% of the control group(χ2=7. 768, P < 0. 05);the shit ball/stem ratio in the observation group was 8. 05%, the bacteria culture dysbacteriosis rate was 0, which were significantly lower than those of the control group ( 35. 63%, 20. 69%)(χ2=19. 393, 20. 077, P < 0. 05);the diarrhea frequency, diarrhoea time, length of hospital stay of the observation group were significantly lower than those of the control group( t=17. 331, 10. 313, 3. 997,P < 0. 05);3, 7 d af-ter treatment, the diamine oxidase level of the observation group was significantly lower than the control group( t=20. 556, 20. 427, P <0. 05). Conclusion Bifidobacterium Tetravaccine Tablets can help alleviate the antibiotic associated diarrhea with clinical symptoms, im-prove the intestinal mucosal barrier function and therapy effect. Targeted nursing can help children recover at an early date.

关键词

思连康/抗生素相关性腹泻/婴幼儿/菌群失调/二胺氧化酶

Key words

Bifidobacterium Tetravaccine Tablets/antibiotic associated diarrhea/infant/dysbacteriosis/diamine oxidase

分类

医药卫生

引用本文复制引用

王妍妍,关晶,温韬雪..思连康改善抗生素相关性腹泻患儿菌群失调随机对照研究[J].中国药业,2016,25(7):5-7,3.

中国药业

OACSTPCD

1006-4931

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