中国药业2016，Vol.25Issue(7)：95-97,3.
基层医院经皮冠状动脉介入治疗术后中断抗血小板药物对预后的影响
Prognosis of Interruption Antiplatelet After PCI with Grassroots Coronary Heart Disease
王振娟 1周树军 1宗文仓 1张立强 1王云梅 1孔令军 1娄志刚1
作者信息
- 1. 河北省玉田县医院，河北 唐山 064199
- 折叠
摘要
Abstract
Objective To evaluate the prognosis of interruption dual antiplatelt therapy after percutaneous coronary intervention ( PCI ) with grassroots coronary heart disease. Methods 180 patients who received drug-eluting stents from 2011 to 2014 were selected and were followed by the cclinical pharmacists. According to the situation of medication, patients were divided into the continuous treatment group ( 138 cases ) and withdrawal group ( 42 cases ) . The incidence of endpoint events were compared between the two groups. Univariate and multivariate COX proportional hazards model were used to analyze the antiplatelet therapy on sustained and with-drawal of endpoint events. Results The major adverse events ( MACE ) and readmissions due to cardiovascular events of the continuous treatment group of were significantly lower than the withdrawal group ( P < 0. 05 ) . Adjustment of risk factors found out than continued drug use was a protective factor of MACE and rehospitalization for cardiovascular events ( P < 0. 05 ); withdrawal is a risk factor of MACE and rehospitalization for cardiovascular events ( P < 0. 05 ) . Conclusion For patients with coronary heart disease and undergoing PCI treatment, the interruption of antiplatelet drugs significantly increases the incidence of cardiovascular events. Continued drug use is a protective factor for cardiovascular events, and the interruption of medication is a risk factor.关键词
抗血小板药物/经皮冠状动脉介入治疗术/心血管事件Key words
antiplatelet drugs/percutaneous coronary intervention/cardiovascular events分类
医药卫生引用本文复制引用
王振娟,周树军,宗文仓,张立强,王云梅,孔令军,娄志刚..基层医院经皮冠状动脉介入治疗术后中断抗血小板药物对预后的影响[J].中国药业,2016,25(7):95-97,3.
