中国中医药信息杂志2016，Vol.23Issue(6)：16-18,3.DOI:10.3969/j.issn.1005-5304.2016.06.005
基于“病证结合”理论探讨溃疡性结肠炎脾肾阳虚证动物模型建立与评价
Discussion on Establishment and Evaluation of Ulcerative Colitis Animal Models with Spleen-kidney Yang Deficiency Pattern Based on the Theory of “Combination of Disease with Syndrome”
摘要
Abstract
Theory of “combination of disease with syndrome” has been widely used in the establishment and evaluation of experimental animal models. The ulcerative colitis animal models with spleen-kidney yang deficiency pattern were established based on the theory according to complex factors. These models were not only required to show the features of “disease” and “syndrome” at the macro characterization, but also combined with microscopic biological indicators and prescription test so as to make comprehensive evaluation. But the problems in the establishment and evaluation of “combination of disease with syndrome” models hindered further development, such as the weak connection between disease and syndrome, multiplicity of models, and limitations in evaluation standards. Therefore, further improvement in the establishment and evaluation of models will make great sense to better ulcerative colitis animal models with spleen-kidney yang deficiency pattern.关键词
溃疡性结肠炎/脾肾阳虚/病证结合/动物模型Key words
ulcerative colitis/spleen-kidney yang deficiency/combination of disease with syndrome/animal models分类
医药卫生引用本文复制引用
郑洁,曹泽标,朱莹..基于“病证结合”理论探讨溃疡性结肠炎脾肾阳虚证动物模型建立与评价[J].中国中医药信息杂志,2016,23(6):16-18,3.基金项目
湖南省教育厅重点课题（13A069）；湖南省科技厅课题（2013SK3080）；长沙市科技计划项目 （）
