中国中医药信息杂志2016，Vol.23Issue(6)：19-22,4.DOI:10.3969/j.issn.1005-5304.2016.06.006
中心性肥胖高血压尿微量白蛋白/尿肌酐特征及与中医证型相关性分析
Analysis on the Characteristics of Urinary Microalbumin/Creatinine Ratio in Central Obesity Hypertension and Its Correlation with Traditional Chinese Medicine Syndromes
摘要
Abstract
Objective To explore the TCM syndrome distribution characteristics of central obesity hypertension patients; To analyze its correlation with urinary microalbumin/creatinine (MA/Cr) ratio; To provide some proof for an efficient way to control central obesity hypertension and prevent and cure its early renal injury with integrated TCM and Western medicine.Methods It was performed in a cross-sectional epidemiological study. The age, gender, height, weight, waist circumference, blood pressure, medical history and symptoms of 359 central obesity hypertension patients were collected in Shanghai. Then according to the four diagnostic methods, TCM syndromes were recorded. The urinary MA/Cr ratio, fasting blood glucose, fasting insulin and hs-CRP levels were detected.Results The urinary MA/Cr detectable rate in Shanghai among central obesity hypertension was 33.4% (120/359), men accounting for 56% and women 44%. Among central obesity hypertension patients, the HOMA-IR and hs-CRP level of urinary albumin group were significantly higher than those of normal group, with statistical significance (P<0.05). Among 359 central obesity hypertension patients, 140 people had phlegm-dampness syndrome, accounting for 39%, the largest part; 108 had liver-yang hyperactivity syndrome, accounting for 30%; 61 had yin-yang deficiency syndrome, accounting for 17%; 50 had yin-deficiency and yang-hyperactivity syndrome, accounting for 14%; the number of four TCM syndromes had statistical difference (P<0.05). Urinary MA/Cr ratio of the patients with phlegm-dampness syndrome was significantly higher than that of other three syndromes (P<0.05).Conclusion The incidence rate of early renal damage with central obesity hypertension patients is high in Shanghai area, and the early stage of renal damage is associated with insulin resistance and inflammatory reaction. Among central obesity hypertension, phlegm-dampness syndrome and liver-yang hyperactivity account for the majority, and patients with phlegm- dampness syndrome are more likely to have early kidney damage.关键词
原发性高血压/中心性肥胖/中医证型/尿微量白蛋白/尿肌酐Key words
primary hypertension/central obesity/TCM syndromes/urinary MA/Cr ratio分类
医药卫生引用本文复制引用
芦波,韩亚楠,周训杰,桂明泰,姚磊,李建华,符德玉..中心性肥胖高血压尿微量白蛋白/尿肌酐特征及与中医证型相关性分析[J].中国中医药信息杂志,2016,23(6):19-22,4.基金项目
上海市进一步加快中医药事业发展三年行动计划（ ZY3-CCCX-3-3026）；高等学校博士学科点专项科研基金（20133107110011）；上海市岳阳中西医结合医院高血压重点专病专科 （）
