中国卒中杂志2016，Vol.11Issue(5)：408-413,6.DOI:10.3969/j.issn.1673-5765.2016.05.015
急性脑出血早期血肿扩大止血治疗研究进展
Hemostatic Therapy on Preventing Hematoma Enlargement in Acute Intracerebral Hemorrhage
摘要
Abstract
Past studies have evidenced the strong relationship between hematoma enlargement after intracerebral hemorrhage (ICH) and early neurological deterioration, indicating poor clinical outcome. Hematoma enlargement is a potentially important therapeutic target. However, hemostatic therapy to all ICH patients indiscriminately does not improve functional outcome, but increases the incidence of arterial thromboembolic adverse events (TAE). Contrast extravasation on CT angiography, namely “spot sign”, predicts hematoma expansion and poor prognosis in acute intracerebral hemorrhage with safety and efficacy. It plays a central role in prevention of early deterioration and improvement of functional outcome to rely on the “spot sign” for the selection of patients to receive early hemostatic therapy with safe and economical hemostatic agents. This study summarizes the related research situation and trend, so as to provide reference for clinical practice.关键词
脑出血/血肿扩大/止血治疗/点样征/预后Key words
Intracerebral hemorrhage/Hematoma enlargement/Hemostatic therapy/Spot sign/Prognosis引用本文复制引用
陈瑶枝,刘丽萍..急性脑出血早期血肿扩大止血治疗研究进展[J].中国卒中杂志,2016,11(5):408-413,6.基金项目
出血性脑血管病诊治及预后干预策略研究（D141100000114002）北京市医院管理局临床医学发展专项经费资助 （）
