中国卒中杂志2016，Vol.11Issue(5)：414-418,5.DOI:10.3969/j.issn.1673-5765.2016.05.016
细胞基质衍生因子-1α在脑梗死中作用的研究进展
Roles of the Stromal Derived Factor-1α in Cerebral Infarction
陈思莹 1段淑荣1
作者信息
- 1. 50001 哈尔滨哈尔滨医科大学附属第一医院神经内科
- 折叠
摘要
Abstract
The chemokine stromal derived factor-1α (SDF-1α) and its receptor C-X-C chemokine receptor type 4 (CXCR4), C-X-C chemokine receptor type 7 (CXCR7) are widely expressed in a variety of cells and tissues, and play an important role in the development of the central nervous system. Recent studies have identiifed that SDF-1α-CXCR4/CXCR7 chemokine axis participates in the process of the angiogenesis after cerebral infarction and endogenous neural stem cells proliferating and migrating to repair the infarction zone, in addition, this axis has affected the inlfammation after cerebral infarction, it may become the new target for the treatment of brain infarction.关键词
脑梗死/细胞基质衍生因子-1α/受体Key words
Cerebral infarction/Stromal cell-derived factor 1α/Receptor引用本文复制引用
陈思莹,段淑荣..细胞基质衍生因子-1α在脑梗死中作用的研究进展[J].中国卒中杂志,2016,11(5):414-418,5.
