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脑源性神经营养因子在中枢神经系统损伤中的多种神经保护作用及其机制的研究进展

籍新潮 徐如祥

中华神经创伤外科电子杂志2016,Vol.2Issue(3):168-172,5.
中华神经创伤外科电子杂志2016,Vol.2Issue(3):168-172,5.DOI:10.3877/cma.j.issn.2095-9141.2016.03.012

脑源性神经营养因子在中枢神经系统损伤中的多种神经保护作用及其机制的研究进展

Resea rch progress of multiple neuroprotective effects of brain-derived neurotrophic factor after central nervous system injury and its mechanism

籍新潮 1徐如祥1

作者信息

  • 1. 100700 北京,陆军总医院附属八一脑科医院
  • 折叠

摘要

Abstract

Brain-derived neurotrophic factor (BDNF) has multiple neuroprotective effects after central nervous system injury, such as inhibiting apoptosis of neurons and oligodendrocytes, promoting the growth of synapse and the regeneration of axon, promoting the regeneration of myelin sheath, adjusting the immune response and nerve excitability after injury, and so on. This article reviewed the possible molecular mechanisms of the neuroprotective effect of BDNF, in order to indentify its application value in the clinic treatment.

关键词

脑源性神经营养因子/神经保护/中枢神经系统

Key words

Brain-derived neurotrophic factor/Neuroprotection/Central nervous system

引用本文复制引用

籍新潮,徐如祥..脑源性神经营养因子在中枢神经系统损伤中的多种神经保护作用及其机制的研究进展[J].中华神经创伤外科电子杂志,2016,2(3):168-172,5.

中华神经创伤外科电子杂志

2095-9141

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