中国现代中药2016，Vol.18Issue(5)：563-567,5.DOI:10.13313/j.issn.1673-4890.2016.5.005
白术利尿作用研究
Study on Diuretic Effect of Atractylodis Macrocephalae Rhizoma
摘要
Abstract
Objective:To study the diuretic effect of the Atractylodis macrocephalae rhizoma and its fractions.Methods:Multi-mode separation methods were adopted to split the components of Atractylodis macrocephalae rhizoma.The indictor of urine excretion in 6 h was used to study the diuretic effect of Atractylodis macrocephalae rhizoma and its splitted fractions in the water loaded rats.Further,the activity of Na +-K +-ATPase in red cell and renal medulla,the level of carbonic anhydrase in renal medulla and the output of Na +,K +,Cl - in urinewere measured to elucidate the related mechanization.Results:The anti-diuretic effect was observed in the high dosage of Atractylodis macrocephalae rhizoma water decoction and volatile oil fraction groups.Versus the control group,the activity of Na +-K +-ATPase in red cell and renal medulla and the level of carbonic anhydrase in renal medulla were not significantly changed in Atractylodis macrocephalae rhizoma water decoction and its fractions groups.Conclusion:The diuretic effect of Atractylodis macrocephalae rhizoma was not observed,instead,the weak antidiuretic effect was presented and it is for the first time that antidiuretic effect of Atractylodis macrocephalae rhizoma volatile oilwas found.关键词
白术/拆分组分/利尿作用Key words
Atractylodis macrocephalae rhizoma/splitted fraction/dieresis引用本文复制引用
陈静,孙云超,冉小库,袁颖,窦德强..白术利尿作用研究[J].中国现代中药,2016,18(5):563-567,5.基金项目
［基金项目］国家重点基础研究计划（973计划）（2013CB531803）；2013辽宁省高等学校创新团队课题 （）
