重庆医学Issue(22)：2599-2602,4.DOI:10.3969/j.issn.1671-8348.2013.22.012
经导管动脉化疗栓塞术治疗41例儿童实体肿瘤的临床研究
Clinical analysis of transcatheter arterial chemoembolization for treating pediatric solid tumors in 4 1 cases
吴艳梅 1胡显良 1王珊 2张利兵 1闫焕 1张英姿 1陈联盟 3谭培兰3
作者信息
- 1. 重庆医科大学附属成都市妇女儿童中心医院儿外科,成都,610091
- 2. 重庆医科大学附属儿童医院肿瘤外科,重庆,400014
- 3. 成都363 医院院放射科,成都,610041
- 折叠
摘要
Abstract
Objective To evaluate the efficacy of transcatheter arterial chemoembolization(TACE)in managements of osteosar-coma,wilms′tumor,hepatoblastoma and huge mixed hemangiomas which can hardly be recected radically during stageⅠ.Methods We retrospectively analyzed 41 cases of solid tumor which can hardly be recected radically during stageⅠfrom Aug 2005 to Aug 2011.All of them underwent TACE,including 5 cases of osteosarcoma,7 cases of Wilms tumor,4 cases of hepatoblastoma,25 cases of huge mixed hemangioma.The shrinkage of solid tumors between pre-operation and post-operation was compared.And the clinical effect was observed.Results 5 cases of osteosarcoma,7 cases of Wilms tumor,4 cases of hepatoblastoma underwent once to three times of TACE before resection.The reduction in volume was 24.9%-36.5%,18.8%-36.9%,43.3%-54.9%;and the mean shrinkage was 25.7%,25.3%,50% respectively.The success rate of radical surgery was 87.5%.Their follow-up periods were sev-en months to sixty-nine months.The result showed the death of two cases and event-free survival of 14 cases.Moreover,25 cases with huge mixed hemangioma were cured by once to four times of TACE.The reduction of huge mixed hemangioma in volume was 44.3%-100%,and the mean shrinkage was 69.4%.The follow-up periods were three months to sixty-one months.The effective rate reached 9 6%.Conclusion The technology of TACE is a safe and effective modality.It can be used as a preoperative therapeutic method in osteosarcoma,Wilms tumor and hepatoblastoma which can hardly be recected radically during stageⅠ.Also it is consid-ered as a preferred modality in curing huge mixed hemangiomas.关键词
实体肿瘤/经导管动脉栓塞化疗/缩小率/根治性手术Key words
solid tumor/transcatheter arterial chemoembolization(TACE)/shrinkage rate/radical surgery引用本文复制引用
吴艳梅,胡显良,王珊,张利兵,闫焕,张英姿,陈联盟,谭培兰..经导管动脉化疗栓塞术治疗41例儿童实体肿瘤的临床研究[J].重庆医学,2013,(22):2599-2602,4.
