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两种肾小球滤过率评价公式评价健康体检人群慢性肾脏病患病率的对比研究

杨沿浪 邹和群 汪裕伟 高潮清 陶青松 金岳龙

南方医科大学学报Issue(9):1347-1351,5.
南方医科大学学报Issue(9):1347-1351,5.DOI:10.3969/j.issn.1673-4254.2013.09.20

两种肾小球滤过率评价公式评价健康体检人群慢性肾脏病患病率的对比研究

Comparison of two equations for calculating glomerular filtration rate in evaluation of the prevalence of chronic kidney disease in healthy population

杨沿浪 1邹和群 2汪裕伟 3高潮清 4陶青松 4金岳龙5

作者信息

  • 1. 南方医科大学附属三院肾脏内科,广东 广州 510603
  • 2. 皖南医学院附属弋矶山医院肾脏内科,安徽 芜湖 241000
  • 3. 南方医科大学附属三院肾脏内科,广东 广州,510603
  • 4. 皖南医学院附属弋矶山医院肾脏内科,安徽 芜湖,241000
  • 5. 皖南医学院附属弋矶山医院检验科,安徽 芜湖,241000
  • 折叠

摘要

Abstract

Objective To compare two equations for calculating glomerular filtration rate (GFR) in the evaluation of the prevalence of chronic kidney disease (CKD) and the risk factors of CKD in urban healthy population. Methods A total of 40377 subjects (24164 males and 16213 females) participated in this study. Body height, weight and blood pressure were measured, and morning urine and venous blood samples were collected for routine urine and blood tests with measurements of blood glucose, total cholesterol, high density lipoprotein (HDL), low-density lipoprotein (LDL), creatinine and uric acid. Results and Conclusion Using Japanese CKD Epidemiology Collaboration (J-EPI) equation and Chinese modified Modification of Diet in Renal Disease (C-MDRD) equation, the prevalence of CKD calculated was 3.9%and 6.3%in this population, respectively. The independent risk factors of CKD included an age over 60 years, high uric acid, and high blood glucose.

关键词

慢性肾脏病/患病率/肾小球滤过率/公式/危险因素

Key words

chronic kidney disease/prevalence/glomerular filtration rate/equation/risk factors

引用本文复制引用

杨沿浪,邹和群,汪裕伟,高潮清,陶青松,金岳龙..两种肾小球滤过率评价公式评价健康体检人群慢性肾脏病患病率的对比研究[J].南方医科大学学报,2013,(9):1347-1351,5.

基金项目

EU FP7 Program, UroSense,2011,安徽省高校自然科学研究基金 ()

南方医科大学学报

OA北大核心CSCDCSTPCDMEDLINE

1673-4254

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