临床与病理杂志2015，Vol.35Issue(1)：43-47,5.DOI:10.3978/j.issn.2095-6959.2015.01.013
非小细胞肺癌患者外周血循环肿瘤细胞与临床特征关系的初步研究
A preliminary study on the relationship between circulating tumor cells count and clinical features in patients with non-small cell lung cancer
摘要
Abstract
Objective:To evaluate the clinical value of circulating tumor cells (CTC) count in peripheral venous blood of patients with non-small cell lung carcinoma (NSCLC).Methods:Totally 50 patients with NSCLC in Wuxi No. 2 people's Hospital were selected for study from January 2013 to December 2013, 35 patients with lung benign tumor and 28 normal volunteers were selected as the control groups. CTC collected from 3 mL venous blood of all people above were counted. Patients with 8.7 units or more CTC were judged to be positive. The relationship between the positive rate of CTC and the age, sex, pathological type and clinical stage was analyzed.Results: CTC count was significantly higher in NSCLC patients than in benign lung patients and healthy controls. CTC count in NSCLC patients was rarely related to the sex, age or the pathological type (P>0.05) and was closely related to clinical stage (P<0.01). Among NSCLC patients, CTC count significantly increased along with tumor progression. Conclusion:The progression of patients with non-small-cell lung carcinoma was associated with the level of CTC count which can relfect the status of the patients to some extent.关键词
循环肿瘤细胞/非小细胞肺癌/临床特征Key words
circulating tumor cells (CTC)/non-small cell lung carcinoma (NSCLC)/clinical features引用本文复制引用
万佳蔚,沈洪远,黄红宇,韩志君,严子禾,高明珠,黄新祥..非小细胞肺癌患者外周血循环肿瘤细胞与临床特征关系的初步研究[J].临床与病理杂志,2015,35(1):43-47,5.基金项目
无锡市医院管理中心医学科技项目(YGZXQ1310).This work was supported by Science and Technology Projects of Wuxi City (YGZXQ1310), P. R. China. （YGZXQ1310）
