海洋科学Issue(8)：28-34,7.
苯并芘B[a]P对泥蚶组织EROD、GST酶活力和MDA含量的影响
Effect of Benzo[a]pyrene on two enzymes activity and lipid peroxidation MAD in Tegillarca granosa
摘要
Abstract
The effects of different concentrations of B[a]P (0.05、0.5、5 and 10μg/L) on EROD, GST and MDA in digestive gland and gills of Tegillarca granosa were studied during 15 days’ exposure to B[a]P. After B[a]P expo-sure, Tegillarca granosa were transferred to fresh seawater to be cultivated for 15 days. The results indicated that the activity of EROD, GST and MDA content were significantly effected in the 0.5, 5 and 10μg/L groups (P<0.05). EROD activity was induced while GST activity was inhibited until the fifth day. MDA content was rising with the treating time and arrived the peak, in the tenth day. All parameters were returned to the control level after 5-10 days’ clearance phase in the fresh seawater. According to our studies, the changes of EROD and GST activity could reflect the body's detoxification metabolism ability. The MDA content showed dose-effect and time-effect relationships, which indicated B[a]P exerted toxic effects on Tegillarca granosa by way of oxidative damage.关键词
苯并(a)芘/泥蚶(Tegillarca granosa)/消化盲囊/鳃丝/EROD/GST/MDAKey words
Benzo[a]pyrene/Tegillarca granosa/digestive gland/gill/EROD/GST/MDA分类
资源环境引用本文复制引用
肖国强,张炯明,邵艳卿,柴雪良,吴洪喜,刘博,方军,滕爽爽..苯并芘B[a]P对泥蚶组织EROD、GST酶活力和MDA含量的影响[J].海洋科学,2013,(8):28-34,7.基金项目
温州市科技计划项目(N20100066) （N20100066）
浙江省近岸水域生物资源开发与保护重点实验室基金项目(J2012006) （J2012006）
