检验医学与临床Issue(14)：1794-1795,1798,3.DOI:10.3969/j.issn.1672-9455.2013.14.009
血清总IgE和外周血嗜酸性粒细胞在特应性皮炎患者检测中的临床意义
Clinical significance of total serum IgE and peripheral blood eosinophil in detection of atopic dermatitis
许志萍1
作者信息
- 1. 广东省广州市第一人民医院皮肤科 510180
- 折叠
摘要
Abstract
Objective To investigate the clinical significance of total serum IgE and peripheral blood eosino-phils (EOS) in detection of atopic derma (AD)and the relationship between total serum IgE ,EOS and AD .Methods 40 cases of AD patients(observation group) and 40 normal cases (control group) in Guangzhou the First People's Hospital from May 2010 to January 2012 were randomly selected .The HITACHI 7170A automatic biochemical tester and the BECKMAN COULTER GEN .S automatic blood cell analyzer were used to detect the total serum IgE and peripheral blood EOS concentration in two groups .Comparison and analysis of the differences between IgE and EOS concentration of two groups and their correlation with AD .Results The total serum IgE and EOS concentration of the observation group were (1 256 .53 ± 1 036 .84) U/mL and (569 .46 ± 322 .13) × 106/L respectively ,which were significantly higher than that of control group (P<0 .05) .The correlation coefficient OR value between IgE and EOS and susceptibility of AD reached 4 .402 and 3 .753 respectively ,the difference was statistically significant (P<0 .05) . There was a significant positive correlation between the degree of AD and IgE and EOS and AD prevalence (P<0 .05) and the correlation coefficient reached 0 .878 and 0 .833 ;the correlation coefficient between IgE and EOS reached 0 .790 ,which showed significant positive correlation (P<0 .05) .Conclusion There is correlation between total serum IgE ,EOS and ocurrence and disease activity in AD ,can provide a basis for AD clinical diagnosis ,therapy and curative effect evaluation .关键词
特应性皮炎/血清总IgE/外周血嗜酸性粒细胞/临床意义Key words
atopic dermatitis/total serum IgE/peripheral blood eosinophil/clinical significance引用本文复制引用
许志萍..血清总IgE和外周血嗜酸性粒细胞在特应性皮炎患者检测中的临床意义[J].检验医学与临床,2013,(14):1794-1795,1798,3.
