中国社区医师2015，Vol.31Issue(12)：38-39,2.DOI:10.3969/j.issn.1007-614x.2015.12.22
多西他赛单药化疗与联合铂类一线治疗老年晚期非小细胞肺癌的有效性与安全性研究
Effective and safety study of docetaxel single agent chemotherapy and combined with platinum based first-line in the treatment of elderly patients with advanced non small cell lung cancer
摘要
Abstract
Objective:To investigate the efficacy and safety of docetaxel combined with cisplatin and single docetaxel in treatment of elderly patients with advanced non small cell lung cancer.Methods:90 aged patients with advanced non small cell lung cancer were selected from 2012 to 2013.They were divided into the observation group and the control group with 45 cases in each group according to the random number table method.We compared the curative effect in the near future of the two groups patients,and evaluated the drug use safety of two groups patients.Results:The comparison of short-term effect of the observation group patients had no difference,and there were no statistical significance(P＞0.05);the observation group patients with bone marrow transplantation,digestive tract reaction rate were higher than those of the control group,and the difference was statistically significant(P＜0.05).Conclusion:The combination of docetaxel and cisplatin and docetaxel in the treatment of elderly patients with advanced non small cell lung cancer,the curative effect difference is not big,but the side effects of drug combination chemotherapy increased significantly in a certain extent,docetaxel single agent chemotherapy is more suitable for elderly patients with advanced non small cell lung cancer.关键词
非小细胞肺癌/多西他赛/顺铂Key words
Non small cell lung cancer/Docetaxel/Cisplatin引用本文复制引用
郭亮,苏克莉,牛建花,牛学才..多西他赛单药化疗与联合铂类一线治疗老年晚期非小细胞肺癌的有效性与安全性研究[J].中国社区医师,2015,31(12):38-39,2.基金项目
2014济南科学技术发展计划(自主创新计划)编号:201401072 （自主创新计划）
