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Livin在人成釉细胞瘤中的表达及其意义研究

范玉 陈钰 钟鸣 郝凤渝

中国实用口腔科杂志Issue(8):463-466,4.
中国实用口腔科杂志Issue(8):463-466,4.

Livin在人成釉细胞瘤中的表达及其意义研究

Expression and significance of Livin in human ameloblastomas

范玉 1陈钰 2钟鸣 1郝凤渝3

作者信息

  • 1. 中国医科大学口腔医学院 病理教研室,沈阳,110002
  • 2. 中国医科大学口腔医学院图书馆,沈阳,110002
  • 3. 中国医科大学口腔医学院修复科,沈阳,110002
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摘要

Abstract

Objective To detect the expression of Livin protein in human meloblastomas(ABs),and to reveal the role of Livin in ABs. Methods By immunohistochemistry ,Western-blot and reverse transcription PCR the expressions of liv-in protein were observed on 80 cases of ameloblastomas tissues. Results The positive expression rate of Livin protein was higher in the star of the network and external layer of cells in ameloblastomas. By Western-blot,compared to normal mucosa,the expression of Livin in ABs was higher than that in normal mucosa(P<0.05);we detected the expression of Livin mRNA expression in ABs by reverse transcription PCR,the expression of Livin in ABs was higher than that in nor-mal mucosa(P<0.05). Conclusion The expression of Livin is associated with AB histogenesis,suggesting that Livin is involved in tumourigenesis.

关键词

成釉细胞瘤/Livin/免疫组化/口腔鳞状细胞癌

Key words

ameloblastomas/Livin/immunohistochemistry/oral squamous cell carcinoma

分类

医药卫生

引用本文复制引用

范玉,陈钰,钟鸣,郝凤渝..Livin在人成釉细胞瘤中的表达及其意义研究[J].中国实用口腔科杂志,2013,(8):463-466,4.

基金项目

国家自然科学基金 ()

中国实用口腔科杂志

OACSTPCD

1674-1595

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