中国医学创新Issue(27)：20-21,22,3.DOI:10.3969/j.issn.1674-4985.2013.27.009
芍药甘草汤治疗利培酮所致高催乳素的临床研究
Clinical Study on Shaoyao Gancao Decoction for Treating Risperidone-induced Hyperprolactinemia
向小妹 1潘彬斌 1李红 1丁跃庆 1桂琴 1虞贝贝 1吴洪军1
作者信息
- 1. 江西省九江市第五人民医院 江西 九江 332000
- 折叠
摘要
Abstract
Objective:To investigate the clinical application value shaoyao-gancao decoction in the treatment of hyperprolactinemia induced by risperidone and its safety.Method:92 psychiatric patients with hyperprolactinemia induced by risperidone from 2011 January to 2012 March in our hospital were analyzed resrospectively(prolactin levels≥1888.5μg/ml),analyzed the indices of plasma concentration of risperidone and 9-hydroxyrisprridone, prolactin,blood concentration,PANSS evaluation were observed in all patients.Result:Compared with before treatment,the serum prolactin level after treatment decreased significantly(P<0.05),but there were no differences in the estradiol,testosterone,progesterone concentrations,the TESS score before and after treatment and the plasma concentration of risperidone and 9-hydroxyrisprridone after treatment.Conclusion:Shaoyao-gancao decoction treatment of risperidone caused by high blood prolactin can rapidly improve the male feminine irregular menstruation,amenorrhea,Male female etc, enhance patient medication adherence,and taking convenient,obvious curative effect,low price,safe and reliable,worthy of clinical popularization and application.关键词
芍药甘草汤/利培酮/高催乳素血症/临床观察Key words
Shaoyao-gancao decoction/Risperidone/Hyperprolactinemia/Clinical observation引用本文复制引用
向小妹,潘彬斌,李红,丁跃庆,桂琴,虞贝贝,吴洪军..芍药甘草汤治疗利培酮所致高催乳素的临床研究[J].中国医学创新,2013,(27):20-21,22,3.
