摘要
Abstract
Objective To investigate the efficacy of edaravone with clopidogrel in the treatment of acute cerebral infarction,and to provide guidance for the clinical. Methods 80 cases with acute cerebral infarction were retrospectively analyzed and selected,the patients were all given intracranial pressure,nutrition brain cells,controlled blood pressure and blood sugar and other symptomatic and supportive treatment.40 patients in the control group were used conventional symptomatic and supportive treatmenton,at the same period,on the basis of the control group,40 patients in the observation group were given edaravone 30 mg plus 250 mL normal saline infusion,2 times a day, clopidogrel 75 mg once a day, orally.Compared the efficacy of the two groups and the nerve function improvement of two groups patients before treatment and after two weeks of treatment. Results After two weeks of treatment, the observation group nerve function improved significant than the control group, there had significant difference(P < 0.05). After two weeks of treatment,the NIHSS of the observation group and the control group were (26.34±7.23),(27.75±8.79) respectively,significantly lower than before treatment, there had significant difference(P<0.05).And the NIHSS of the observation group after treatment 2 weeks decreased more significantly than the control group,there were significant differences (P<0.05). Conclusion Edaravone with clopidogrel in the treatment of acute cerebral infarction have better clinical efficacy,little adverse reactions,significant improvement in the prognosis of patients,and it is worthy to use in primary hospital.关键词
急性脑梗死/依达拉奉/氯吡格雷/NIHSSKey words
Acute cerebral infarction/Edaravone/Clopidogrel/NIHSS分类
医药卫生
