中国医药科学Issue(16)：215-216,2.
10日序贯疗法与四联疗法治疗幽门螺杆菌感染疗效对比分析
Curative effect analysis of 10 days sequential therapy and quadruple therapy in treatment of helicobacter pylori infection
王宏彦 1徐宝宏 2吴海波1
作者信息
- 1. 北京市通州区张家湾卫生院,北京,101113
- 2. 北京市通州区潞河医院,北京,101149
- 折叠
摘要
Abstract
Objective To investigate the curative effect comparison of 10 days sequential therapy and quadruple therapy in treatment of helicobacter pylori infection. Methods 42 cases of helicobacter pylori infection were randomly selected as control group,and were given quadruple therapy:1000mg amoxicillin + 500mg clarithromycin+ 20mg omeprazole + 220mg bismuth potassium citrate, Bid, for 10 days; 43 cases of helicobacter pylori infection were randomly selected as treatment group, and were given 10 days sequential therapy:1000mg amoxicillin+20mg omeprazole for the first 5 days,Bid,and 400mg metronidazole+500mg clarithromycin+omeprazole 20 mg for the next 5 days,Bid. Results After treatment for 10 days, stop PPI and antibiotics for 4 weeks, negative 13C-UBT test means helicobacter pylori (H.p ylori) was cured successfully. Experiment results showed that 33 cases of the control group were cured successfully, eradication rate was 78.6%(33/42);40 cases of the treatment group were cured successfully, eradication rate was 93.0% (40/43). Differences of two groups was statistically significant by statistical analysis (P < 0.05). Conclusion The experiment results show that treatment methods of two groups in treatment of helicobacter pylori infection both are effective, curative effect is better of the treatment group,which has the vital clinical significance.关键词
10日序贯疗法/四联疗法/幽门螺杆菌Key words
10 days sequential therapy/Quadruple therapy/Helicobacter pylori分类
医药卫生引用本文复制引用
王宏彦,徐宝宏,吴海波..10日序贯疗法与四联疗法治疗幽门螺杆菌感染疗效对比分析[J].中国医药科学,2013,(16):215-216,2.
