中国卒中杂志Issue(9)：723-728,6.
性别、年龄、卒中类型与卒中后失语症类型的相关性分析
Effects of Sex, Age and Types of Stroke on Post-stroke Aphasia
摘要
Abstract
Objective To explore the association between the types of aphasia and sex, age and stroke types. <br> Methods Four hundred and twenty-one aphasiacs after stroke who met the inclusion and exclusion criteria and were admitted to Department of Neurology of Beijing Tiantan Hospital, Capital Medical University from July 2005 to July 2012 were restrospectively analyzed. The criteria of handedness instituted by Peking University First Hospital was used to judge patients' handedness. Western battery aphasia was used to assess the aphasiac type and calculate Aphasia Quotient (AQ) score. Patients were divided into youth, middle-aged and elderly groups, and stroke types include cerebral infraction (CI) and intracerebral hemorrhage (ICH). Finally we analyzed the types of aphasia in different ages, sex and stoke types. <br> Results All subjects were dextromanual, in whom males and females accounted for 69.60%and 30.40%, respectively. The types of aphasia included Broca's aphasia (male 85, female 31), Wernicke's aphasia (male 20, female 15), conductive aphasia (male 10, female 5), transcortical motor aphasia (male 50, female 13), transcortical sensory aphasia (male 8, female 3), transcortical combined aphasia (male 13, female 14), anomic aphasia (male 47, female 26) and global aphasia (male 60, female 21). Male patients (69.60%) have a signiifcantly higher level of morbidity of aphasia than females (30.40%) after stroke (χ2=11.57, P=0.003), especially those under 65 years old (73.38%). After 65 years old, the morbidity of female tends to increase with age (42.97%). Sex has no remarkable effect on the types of aphasia (χ2=13.84, P=0.054), Broca's aphasia is the most common types in both males and females (29.01%, 24.22%, respectively). The distribution of aphasic types has no obvious difference among three age groups (χ2=14.94, P=0.382). Aphasia induced by CI (306 cases) is more common than by ICH (115 cases), but the distribution of types of aphasia has no difference (χ2=13.23, P=0.067). Broca's aphasia is the most common aphasic type in both CI and ICH patients (29.82%, 29.55%, 26.67%, respectively), except the females with ICH. <br> Conclusion Age, sex and stroke types have no signiifcant inlfuence on the types of aphasia. Male patients have a signiifcantly higher level of morbidity of aphasia than females after stroke as well as the average age of onset is younger than females. Broca's aphasia is the most common one in both males and females. Broca's aphasia, global and anomic aphasia are the most aphasic types in both CI and ICH patients, except the females with ICH.关键词
卒中/失语症类型/性别/年龄/卒中类型Key words
Stroke/Type of aphasia/Sex/Age/Type of stroke引用本文复制引用
姚婧璠,宋彦丽,李磊,周筠,王春雪,王拥军,张玉梅..性别、年龄、卒中类型与卒中后失语症类型的相关性分析[J].中国卒中杂志,2013,(9):723-728,6.基金项目
北京师范大学认知神经科学与学习国家重点实验室办公室开放课题、国家社科基金重点项目（11AZD119）北京市卫生系统高层次卫生技术人才培养计划（2011-3-024）国家社科基金重大项目（11&ZD186）北京市科委脑卒中急性期四项内科关键诊疗技术规范研究（D101107049310005）缺血性脑血管病患者二级预防、康复技术的综合疾病管理模式的推广（Z131100002613005）国家科技支撑计划项目 （）
