中山大学学报（自然科学版）Issue(5)：123-126,129,5.
复方血栓通胶囊中4个有效成分的一测多评定量方法研究*
A Quantitative Method Using One Marker for Simultaneous Assay of Four Effective Components in Compound Xueshuantong Capsule
摘要
Abstract
The paper reported the establishment of a quantitative method for simultaneously determining four effective components in Compound Xueshuantong capsule by using one chemical reference,the new quality evaluation method,quantitative analysis of multi-components by single marker (QAMS),using Ginsenoside Rg1 as the internal reference substance,was developed by HPLC to simultaneously determine Notoginsenoside R1 ,Ginsenoside Rg1 ,Ginsenoside Re,Ginsenoside Rb1 in Compound Xueshuantong capsule with the relative correction factor (RCF).In addition,the results of QAMS method were valida-ted by comparing with that of external standard method.The results show that the RCFs have good repro-ducibility and no significant differences between the quantitative results of QAMS method and external standard method were observed.So,it is a accurate,convenient and practical method to simultaneously determine four effective components in Compound Xueshuantong capsule for its quality control.关键词
复方血栓通胶囊/一测多评/校正因子/高效液相色谱法Key words
Compound Xueshuantong capsule/QAMS/relative correction factor/HPLC分类
医药卫生引用本文复制引用
梁洁萍,陈思,谢称石,彭维,苏薇薇..复方血栓通胶囊中4个有效成分的一测多评定量方法研究*[J].中山大学学报（自然科学版）,2013,(5):123-126,129,5.基金项目
国家“重大新药创制”科技重大专项资助项目（2011ZX09201-201-22）；国家科技支撑计划课题（2012BAI29B09）；东莞医疗卫生科技计划资助项目 （）
