安徽医科大学学报2016，Vol.51Issue(7)：1011-1014,4.
呼吸道感染儿童九项呼吸道病原体 IgM 抗体结果分析
IgM antibodies against 9 kinds of respiratory pathogens in children with respiratory infectious diseases
摘要
Abstract
Objective To investigate the epidemiological characteristics of IgM antibodies against 9 kinds of respir-atory pathogens in children so as to provide evidence for clinically effective prevention and treatment .Methods On 1 454 children with respiratory infectious diseases in hospital , IgM antibodies against legionella pneumophila (LP1), mycoplasma pneumoniae(MP), q fever coxiella burnetii(COX), chlamydia pneumoniae(CPn), adenovi-rus(ADV), respiratory syncytial virus(RSV), influenza A virus(INFA), influenza B virus(INFB) and parainflu-enza virus(PIVs) were measured by indirect immunofluorescence assay .The positive rate of IgM antibodies and its seasonal distribution were observed .Results Among 1 454 cases, there were total 729 positive cases of IgM anti-bodies against 9 kinds of respiratory pathogens and the positive rate was 50.14%.The positive rate of MP was high-est, followed by INFB, ADV, RSV and PIVs.The positive rates of MP and INFB in girls were significantly higher than it in boys(P <0.01).In different age groups, the positive rates of IgM antibodies against respiratory tract pathogens were different and the positive rate was highest in 3 ~7 years old group, in which positive rates of IgM antibodies against MP and INFB were 55.7% and 33.76% , which were significantly higher than the positive rate of infection in children in other age groups(P <0.01).In a year, the positive rates of IgM antibodies against MP , PIVs, RSV, INFB, LP1 and ADV were highest in May, which were 59.49%, 14.56%, 13.29%, 43.67%, 5.06% and 30.38% respectively.Conclusion Children with respiratory infectious diseases are mainly infected by MP and INFB and positive rate in girls is significantly higher than that in boys .The children between 3 and 7 years old are the high-risk population with respiratory infectious diseases .关键词
呼吸道感染/呼吸道病原体/儿童Key words
respiratory infectious/respiratory pathogens/child分类
医药卫生引用本文复制引用
李涛,徐恩君,陈秋莉,郝丽,肖春红,徐元宏,周敏,徐胜前..呼吸道感染儿童九项呼吸道病原体 IgM 抗体结果分析[J].安徽医科大学学报,2016,51(7):1011-1014,4.基金项目
国家自然基金(30801088、81201488、81571572) ,卫生部应用研究项目,“高通量 ELISA 检测系统化、标准化系列研究”(28－1－50) （30801088、81201488、81571572）
