法医学杂志2016,Vol.32Issue(3):204-210,7.DOI:10.3969/j.issn.1004-5619.2016.03.011
人体生物性物质来源鉴定及法医学应用研究进展
Source Identification of Human Biological Materials and Its Prospect in Forensic Science
摘要
Abstract
Source identification of human biological materials in crime scene plays an important role in reconstructing the crime process. Searching specific genetic markers to identify the source of different human biological materials is the emphasis and difficulty of the research work of legal medical experts in recent years. This paper reviews the genetic markers which are used for identifying the source of human biological materials and studied widely, such as DNA methylation, mRNA, microRNA, microflora and protein, etc. By comparing the principles and methods of source identification of human biological materials using different kinds of genetic markers, different source of human biological material owns suitable marker types and can be identified by detecting single genetic marker or combined multiple genetic markers. Though there is no uniform standard and method for identifying the source of human biological materials in forensic laboratories at present, the research and development of a series of mature and reliable methods for distinguishing different human biological materials play the role as forensic evi-dence which will be the future development direction.关键词
法医遗传学/遗传标记/综述[文献类型]/来源Key words
forensic genetics/genetic markers/review [publication type]/source分类
社会科学引用本文复制引用
邹凯南,桂程,曹禹,杨帆,周怀谷..人体生物性物质来源鉴定及法医学应用研究进展[J].法医学杂志,2016,32(3):204-210,7.基金项目
上海市科学技术委员会科研计划项目(14JG0500400) (14JG0500400)