摘要
Abstract
Objective:To observe the clinical curative effect of Dahuang (Radix et Rhizoma Rhei) in combination with ulinastatin on acute pancreatitis (AP).Methods:One hundred and five patients with AP who were treated in our hospital between Jan.of 2011 and Jan.of 2016 were chosen as the research objects,and randomly group,divided into the control group,DH1 group,DH2 group,DH3 group,DH4 group,DH5 group,and DH6 group,with 15 cases in each group.The ones in the control group were given routine internal symptomatic treatment,while the ones in the DHI group,DH2 group,DH3 group were added Dahuang fluid for nasal jejunal tube perfusion method based on the treatment of the control group.The drug dose of DH1 group 1 was taken once a day;For DH2 group,once every 12 hours and twice a day;For DH3 group,once every 8 hours and three times a day;For DH4 group,DH5 group,and DH6 groups,Dahuang fluid were added for gastric perfusion,and for DH4 group,once a day;For DH5 group,once every 12 hours and twice a day;For DH3 group,once every 8 hours and three times a day.Then each group's AMS recovery time,abdominal signs disappearing time and the intestinal function recovery time,TNF-α and IL-6 levels before and after treatment were observed.Results:AMS recovery time,abdominal signs disappearing time and the intestinal function recovery time,TNF-α and IL-6 levels of DH3 group were all better than those of DH1 group,DH2 group,and the control group (P ＜ 0.05).Those of DH2 group were all better than those of the control group,DH1 group,and DH2 group (P ＜ 0.05).Each clinical observed index improvement of DH3 which was treated with nasal jejunal tube perfusion method was better than that of DH6 group which was treated with gastric perfusion (P ＜ 0.05).Conclusion:Using 30g of Dahuang for nasal jejunal tube perfusion in combination with ulinastatin has a better clinical curative effect on AP.关键词
急性胰腺炎/大黄/乌司他丁/不同剂量/不同给药途径Key words
acute pancreatitis (AP)/Dahuang (Radix et Rhizoma Rhei)/ulinastatin/different doses/different drug-taking methods分类
医药卫生
