临床眼科杂志2016，Vol.24Issue(3)：200-202,3.DOI:10.3969/j.issn.1006-8422.2016.03.003
全视网膜激光光凝对角膜基底下神经纤维密度的影响
The effects of panretinal photocoagulation on corneal subbasal nerve density
崔浩 1陈志杰 1王爽 1张秀娟 1刘江 1蔡晓松1
作者信息
摘要
Abstract
Objective To analyze the effects of panretinal photocoagulation ( PRP) on changes in corneal subbasal nerve density in patients with ischemic type of center retinal vein occlusion ( CRVO) .Methods Ischemic CRVO patients ( n =20) accepted PRP and age and gender matched normal subjects ( n =20) were enrolled as control .Before and after treatment, in vivo confocal microscopy (IVCM) was used to obtain images for subbasal dendritic cells .Cell density was measured using NeuronJ software .Corneal sensitivity was tested using the Cochet-Bonnet esthesiometer .Data were analyzed with t-tests or χ2 test.Results After 6 months of the treatment , corneal subbasal nerve density was significantly lower in ischemic CRVO patients (10178 ±6109) than in normal subjects (18302 ±4991;P <0.05).Corneal sensitivity also re-duced after PRP and the difference between the two groups was significant ( P <0.05).Conclusions Patients accepted PRP showed a significant reduction in corneal subbasal nerve density .关键词
显微镜检查,共焦/角膜/视网膜静脉闭塞/全视网膜激光光凝Key words
In vivo confocal microscopy/Cornea/Tetinal vein occlusion/Panretinal photocoagulation引用本文复制引用
崔浩,陈志杰,王爽,张秀娟,刘江,蔡晓松..全视网膜激光光凝对角膜基底下神经纤维密度的影响[J].临床眼科杂志,2016,24(3):200-202,3.
