中国临床保健杂志2016，Vol.19Issue(4)：343-345,3.DOI:10.3969/J.issn.1672-6790.2016.04.002
新疆维吾尔族、汉族老年人轻度认知功能障碍与血浆同型半胱氨酸水平的相关性
Correlation study between mild cognitive impairment and homocysteine of Uygurs and Hans aged in Xinjiang
摘要
Abstract
Objective To explore the association between mild cognitive impairment and plasma homocys-teine of Uygurs and hans aged in Xinjiang.Methods A total of 5398 Uygurs and Hans aged 60 years or older were surveyed in south,east and north of Xinjiang by divided-levels,random,cluster sampling approaches a ccording to the DSM-IV(Diagnostic and Statistical Manual of Mental Disorders,forth version).Based on the epidemiological investiga-tion,the case-control anlaysis had been adopted.We selected 314 patients with MCI as MCI group (161 Uygurs,153 Hans)and 299 normal elderly people as control group (149 Uighurs,150 Hans);plasma homocysteine of two groups were compared.Results Plasma homocysteine of MCI group was significant higher than that in the control group (P <0.05),and the result was same in Uygurs and Hans respectively(P <0.01).Plasma homocysteine of MCI group was higher than the control group in different ages (P <0.05),and the homocysteine was gradually increased with age (P <0.05 ).Plasma homocysteine of male and female in MCI group was higher than that in control group (P <0.05).Conclusion Plasma homocysteine relates with the pathogenesis in aged with MCI in Xinjiang ,and increased with age.High plasma homocysteine is an independent risk factor of aged with MCI in Xinjiang,China.关键词
轻度认知障碍/半胱氨酸/维吾尔族/汉族/危险因素Key words
Mild cognitive impairment/Cysteine/Uygur nationality/Han nationality/Risk factors分类
医药卫生引用本文复制引用
邹婷,朱梅生,周晓辉,苗海军,张雷..新疆维吾尔族、汉族老年人轻度认知功能障碍与血浆同型半胱氨酸水平的相关性[J].中国临床保健杂志,2016,19(4):343-345,3.基金项目
国家自然科学基金资助项目 （）
