中国临床保健杂志2016，Vol.19Issue(4)：346-348,3.DOI:10.3969/J.issn.1672-6790.2016.04.003
再灌注损伤在急性心肌梗死合并低血压及心源性休克中的临床意义和治疗对策
Clinical significance and treatment of reperfusion injury in acute myocardial infarction patients with hypoten-sion and cardiogenic shock
摘要
Abstract
Objective To explore the clinical significance and treatment of reperfusion injury in acute myocar-dial infarction (AMI)with hypotension and cardiogenic shock.Methods One hundred and thirty -one AMI patients with hypotension and cardiogenic shock who were undergoing emergency PCI were collected.According to the occurring or worsening of hypotension and cardiogenic shock after reperfusion,45 patients were divided into treatment group,and the other 86 patients were divided into control group.To analyze the clinical manifestations of myocardial ischemia reper-fusion injury and the efficacy of emergency PCI supported by sequential therapy with optimized vasopressors and IABP in both groups.Results After reperfusion,45 patients (34.35% )were occurred or worsen of hypotension and cardiogen-ic shock as treatment group;86 patients (65.65%)as control group.There were 100 cases of reperfusion arrhythmia (76.34%)in both groups,including 43 cases of accelerated idioventricular rhythm,31 cases of bradyarrhythmia,23 ca-ses of premature ventricular contraction,and 3 cases of ventricular fibrillation.The fatality rate and cardiovascular event (such as left ventricular failure)rate were no statistically significant difference between the treatment group and the con-trol group.However,the number of patients that must use IABP of treatment group was significantly lower than control group (P <0.05).Conclusion Reperfusion injury is one of the leading causes of AMI with hypotension and cardiogen-ic shock.It can be treated with emergency PCI supported by sequential therapy with optimized vasopressors and IABP.关键词
心肌梗死/再灌注损伤/休克,心源性/血管成形术,气囊,冠状动脉/低血压Key words
Myocardial infarction/Reperfusion injury/Shock,cardiogenic/Angioplasty,balloon,coronary/Hy-potension分类
医药卫生引用本文复制引用
张科林,郭战宏,龙丽辉,蔡天志,刘佰学,辛宏..再灌注损伤在急性心肌梗死合并低血压及心源性休克中的临床意义和治疗对策[J].中国临床保健杂志,2016,19(4):346-348,3.基金项目
陕西省教育厅科研基金项目 （）
