中国临床保健杂志2016，Vol.19Issue(4)：389-392,4.DOI:10.3969/J.issn.1672-6790.2016.04.018
促性腺激素释放激素激动剂联合左炔诺孕酮宫内节育系统用于子宫内膜异位症术后效果
Effect of GnRH-a combined with levonorgestrel intrauterine system for postoperative endometriosis patients
摘要
Abstract
Objective To explore the effect of GnRH-a combined with Levonorgestrel intrauterine system in postoperative of endometriosis patients.Methods Fifty-six patients with endometriosis were collected and the treatment group and the contrast group by random number table method.Patients in the control group received the GnRH-a,and the contrast group received the GnRH-a combined with Levonorgestrel intrauterine system.The patients of two groups were followed up for one year.The dysmenorrhea score and serum CA125 are compared,and the rates of efficient and re-currence of two groups were evaluate and compared.Results The dysmenorrhea score and CA125 were lower than the preoperative (P <0.05).There was no significant difference between 1 year and postoperative 3 months,6 months,9 months (P >0.05),while the dysmenorrhea score and serum CA125 of control group at one year after operation are sig-nificantly higher than 3 months,6 months and 9 months after operation,the difference was statistically significant (P <0.05).The obsever group efficiency (82.14%),significantly higher than that in control group efficiency (64.29%), compared the two groups had a significant difference (P <0.05).The obsever group recurrence rate (7.14%),signifi-cantly lower than that in control group efficiency (39.29%),compared the two groups had a significant difference (P <0.05).Conclusion GnRH-a combined with Levonorgestrel intrauterine system can effectively improve the patient's pain,reduce the postoperative recurrence,improve the clinical curative effect among patients with endometriosis;is a kind of effective consolidation treatment.关键词
子宫内膜异位症/左炔诺孕酮/促性腺素释放激素/痛经/复发Key words
Endometriosis/Levonorgestrel/Gonadotropin-releasing hormone/Dysmenorrhea/Recurrence分类
医药卫生引用本文复制引用
张岩,杨飚,徐文萍,张安乐,蒋莉莉..促性腺激素释放激素激动剂联合左炔诺孕酮宫内节育系统用于子宫内膜异位症术后效果[J].中国临床保健杂志,2016,19(4):389-392,4.基金项目
安徽省科技攻关项目 （）
