中国临床保健杂志2016，Vol.19Issue(4)：392-394,3.DOI:10.3969/J.issn.1672-6790.2016.04.019
巨噬细胞移动抑制因子在诊断老年肾病综合征合并脑梗死患者的临床应用
Clinical application of MIF in the diagnosis of elderly nephrotic syndrome patients with cerebral infarction
王小永 1于翔 1李永强 1王军文 1任敏1
作者信息
- 1. 陕西宝鸡市中心医院神经内科，721008
- 折叠
摘要
Abstract
Objective To study the clinical application of MIF in the diagnosis of elderly nephrotic syndrome patients with cerebral infarction.Methods Clinical data of 84 patients with nephrotic syndrome were analyzed,ne-phrotic syndrome patients with cerebral infarction as the observation group,patients with nephrotic syndrome as con-trol group.MIF were measured by ABC-ELISA.Results The TG in the observation group was significantly higher than that in control group(t =2.792,P =0.007).No significant difference was found between the two groups in TC, HDL and LDL-C (P >0.05).Serum Hcy (t =2.601,P =0.011),MIF (t =2.973,P =0.004),and hs-CRP(t =2.143,P =0.035)in the observation group were higher than those in control group,a statistically significant differ-ence (P <0.05).TG had a positive correlation with Hcy (r =0.365,P =0.020),MIF(r =0.477,P =0.002), hs-CRP(r =0.357,P =0.024)in observation group.When the MIF value was 0.856 μg/L,the sensitivity of the di-agnosis of nephrotic syndrome with cerebral infarction was 92.52%,specificity was 88.64%.Conclusions MIF <br> can be used as a effective index in the clinical diagnosis of nephrotic syndrome patients with cerebral infarction.关键词
肾病综合征/脑梗死/巨噬细胞移动抑制因子Key words
Nephrotic syndrome/Cerebral infarction/Macrophage migration inhibitory factor分类
医药卫生引用本文复制引用
王小永,于翔,李永强,王军文,任敏..巨噬细胞移动抑制因子在诊断老年肾病综合征合并脑梗死患者的临床应用[J].中国临床保健杂志,2016,19(4):392-394,3.
