环境与职业医学2016，Vol.33Issue(6)：557-561,5.DOI:10.13213/j.cnki.jeom.2016.16152
液相芯片技术检测糖尿病患者血清中的多重脂肪因子:应用与优势
Detection of Multiple Serum Adipokines in Patients with Type 2 Diabetes Mellitus Using Multiplex Analysis Technology: Application and Advantages
摘要
Abstract
[Objective] To detect the levels of multiple serum adipokines in elderly patients with type 2 diabetes and healthy controls by multiplex analysis technology.[Methods] A total of 28 cases of elderly patients with type 2 diabetes mellitus (T2DM) and 22 cases of healthy controls were recruited in this study.Levels of serum multiple adipokines including adiponectin,resistin,adipsin,lipocalin-2,and plasminogen activator inhibitor-1 (PAI-1) were detected by the Magpix liquid chip instrument.The difference of the levels between the two groups was analyzed.[Results] Only serum PAI-1 level of the T2DM group was 1.29times that of the control group (P＜0.05),whereas other four adipokines had no differences (P＞0.05).[Conclusion] PAI-1 level is closely associated with glycometabolism.Multiplex analysis technology facilitates chronic disease biomonitoring and control.关键词
液相芯片技术/Magpix液相芯片仪/2型糖尿病(T2MD)/脂肪因子Key words
multiplex analysis technology/Magpix liquid chip instrument/type 2 diabetes mellitus (T2DM)/adipokine分类
医药卫生引用本文复制引用
何欣,陆晔,朱佩云,廖萍,刘茶珍,王文静..液相芯片技术检测糖尿病患者血清中的多重脂肪因子:应用与优势[J].环境与职业医学,2016,33(6):557-561,5.基金项目
上海市卫生和计划生育委员会面上项目(编号:201440617) （编号:201440617）
