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PM2.5的肺毒性机制研究进展

杨洁 邓建军 刘靳波 张开炯

环境与职业医学2016,Vol.33Issue(6):615-619,5.
环境与职业医学2016,Vol.33Issue(6):615-619,5.DOI:10.13213/j.cnki.jeom.2016.15600

PM2.5的肺毒性机制研究进展

Research Progress on Lung Toxicity Mechanism of Fine Particulate Matters

杨洁 1邓建军 1刘靳波 2张开炯1

作者信息

  • 1. 泸州医学院临床检验系,四川 泸州 646000
  • 2. 四川绵阳四○四医院临床检验科,四川 绵阳 621000
  • 折叠

摘要

Abstract

Exposure to atmospheric fine particulate matters (PM2.5) has already been recognized as a major public health problem.It can cause muhiple adverse health effects,especially lung diseases.In this light,recent studies reporting ingredients potential mechanism of human lung toxicity induced by PM2.5 exposure were reviewed in this article and presented in four categories including inflammatory response,oxidative stress,immune toxicity,and genetic mutations.This review aimed to provide a theoretical basis for further related study and the diagnosis of lung toxicity induced by PM2.5.

关键词

细颗粒物(PM2.5)/肺毒性机制/炎症作用/氧化应激/免疫毒性/基因突变

Key words

fine particulate matter (PM2.5)/lung toxicity/inflammatory response/oxidative stress/immune toxicity/genetic mutation

分类

医药卫生

引用本文复制引用

杨洁,邓建军,刘靳波,张开炯..PM2.5的肺毒性机制研究进展[J].环境与职业医学,2016,33(6):615-619,5.

基金项目

国家自然科学基金项目(编号:414720416) (编号:414720416)

四川省科技计划项目(编号:2016JY0045) (编号:2016JY0045)

环境与职业医学

OA北大核心CSCDCSTPCD

2095-9982

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