世界中医药2016，Vol.11Issue(6)：982-985,4.DOI:10.3969/j.issn.1673-7202.2016.06.011
黄芪注射液对Ⅲ期胃癌的疗效及对机体免疫功能的影响
The Effect of Huangqi Injection on Stage III Gastric Carcinoma and its Function on Bodys Immunity
摘要
Abstract
Objective:To observe the curative effect of Huangqi injection on stage III gastric cancer and its effects on the bodys immune function.Methods:A total of 60 patients in stage III gastric carcinoma admitted in our hospital during January 2009 to January 2014 were randomly divided into the control group and the observation group.Also,30 cases of healthy people were recrui-ted as healthy control group.Both of the two groups had received radical operation and took the conventional EOF scheme chemo-therapy after surgery.The observation group was given Huangqi injection 30 mL with 250 mL 0.9% sodium chloride solution by in-travenous drip on the basis of conventional treatment,1 time /day,20 days.After treatment,compared the two groups in the aspects of quality of life (Karnofsky score),peripheral blood mononuclear cells,and the accumulative survival rate.Detected the peripheral blood Th1,Th2,and the cell percentage change of the three groups.Results:1 )Huangqi injection could obviously increase the quality of life in the patients in stage III gastric cancer,and simultaneously increase the accumulative survival rate of the patients. 2)Th1 /Th2 ratio in the patients with gastric cancer was significantly lower than that of the healthy control group.However,Th1 /Th2 ratio of the two groups both decreased after treatment,and the descending trend in the observation group was more obvious (P<0.05).Conclusion:For patients in stage III gastric carcinoma,CD4 +T cells are abnormal and Huangqi injection can improve the quality of the patientslife by regulating the levels of CD4 +T cells.关键词
Ⅲ期胃肿瘤/黄芪注射液/Th1 /Th2Key words
Stage III gastric carcinoma/Huangqi injection/Th1 /Th2 ratio分类
医药卫生引用本文复制引用
赵为民,刘林,方法,杨新辉,王海江..黄芪注射液对Ⅲ期胃癌的疗效及对机体免疫功能的影响[J].世界中医药,2016,11(6):982-985,4.基金项目
新疆卫生厅医疗卫生科研计划项目 （）
