世界中医药2016，Vol.11Issue(6)：1131-1136,6.DOI:10.3969/j.issn.1673-7202.2016.06.052
雌激素或雌激素样物质对心血管系统的影响及其作用途径与机制
Effects of Estrogen and Estrogenic Compounds on Cardiovascular System and its Pathway and Mechanism
摘要
Abstract
The increasing incidence of female menopausal cardiovascular disease is closely related to the decline of the levels and hypofunction of estrogen.As an important steroid hormone,estrogen has widely distributed targets and complex biological effects.It enrolls in the regulation of the functions of multiple organs and systems.Estrogen or estrogenic compounds exert their biological effects through the non-genomic and genomic pathways via the typical estrogen receptor (ER)αand ERβor G protein coupled es-trogen receptor (GPER).The research of estrogen on cardiovascular system via ER pathway and its mechanisms will present as an important reference for the clinical treatment of female menopausal cardiovascular disease.This paper will discuss mainly on the role and its mechanisms of estrogen or estrogenic compounds on cardiovascular system.关键词
雌激素/雌激素受体/G蛋白偶联雌激素素受体/心血管疾病/雌激素替代治疗Key words
Estrogen/Estrogen receptor/G protein coupled estrogen receptor/Cardiovascular disease/Estrogen replacement therapy分类
医药卫生引用本文复制引用
臧金凤,赵丕文,陈梦,武虹波,赵笛,牛建昭..雌激素或雌激素样物质对心血管系统的影响及其作用途径与机制[J].世界中医药,2016,11(6):1131-1136,6.基金项目
国家自然科学基金项目（编号81273887）；高等学校创新引智计划（编号B07007）；北京中医药大学自主科研课题 （）
