色谱2016，Vol.34Issue(7)：673-680,8.DOI:10.3724/SP.J.1123.2016.03001
前吸附技术-超高压液相色谱-串联质谱法同时测定酒中24种邻苯二甲酸酯
Simultaneous determination of 24 phthalates in liquors using front adsorption technology and ultra performance liquid chromatography-tandem mass spectrometry
摘要
Abstract
A method for the simultaneous determination of 24 phthalates in liquors was developed by using front adsorption technology and ultra performance liquid chromatography-tandem mass spectrometry( UPLC-MS/MS ). The samples were diluted and cleaned-up by an HLB solid phase extraction cartridge. The front adsorption technology was used to suppress the interferences which came from plastic pipes in the UPLC-MS/MS. And then the targets were analyzed by UPLC-MS/MS under the positive ion mode using multiple reaction monitoring ( MRM)mode. The calibration curves showed a good linearity in the range of 0. 005-2. 00 mg/L with r﹥0. 99. The limits of detections ( S/N = 3 ) were 0. 003-0. 05 mg/kg. The average recoveries of the spiked samples were between 75. 4% and 118. 2% with the relative standard deviations( RSDs)of 4. 0%-11. 2%. The method could be used to simultaneously confirm the multi-residue of the 24 phthalates in liquors. And the method is simple,sensitive and stable.关键词
超高压液相色谱-串联质谱/前吸附技术/邻苯二甲酸酯/酒Key words
ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)/front adsorbing technology/phthalates/liquors分类
化学化工引用本文复制引用
吴敏,郑向华,张志刚,陈燕,林立毅,黄志强..前吸附技术-超高压液相色谱-串联质谱法同时测定酒中24种邻苯二甲酸酯[J].色谱,2016,34(7):673-680,8.基金项目
“十二五”国家科技支撑计划项目（2012BAK08B01）；福建省自然科学基金项目（2014J01057）．@@@@National Key Technology R＆D Program during the Twelfth Five-year Plan Period（ No．2012BAK08B01）；Natural Science Foundation of Fujian Province（ No．2014J01057）． （）
