中国当代儿科杂志2016，Vol.18Issue(7)：607-613,7.DOI:10.7499/j.issn.1008-8830.2016.07.008
13 198例急性呼吸道感染住院患儿肺炎支原体、肺炎衣原体及嗜肺军团菌分布特点分析
Distribution characteristics of Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila in hospitalized children with acute respiratory tract infection：an analysis of 13198 cases
摘要
Abstract
Objective To investigate the distribution characteristics of Mycoplasma pneumoniae (MP), Chlamydia pneumoniae (CP), and Legionella pneumophila (LP) in hospitalized children with acute respiratory tract infection (ARTI). Methods A total of 13198 hospitalized children with ARTI were enrolled as study subjects. Whole blood and urine were collected. The passive agglutination was used to detect serum MP-IgM, ELISA was used to detect serum CP-IgM, and immunochromatography was performed to detect urinary LP antigen. Results Among the 13198 hospitalized ARTI children, the detection rates of MP, CP, and LP were 25.31%, 12.74% and 3.27%, suggesting that MP had the highest detection rate (P<0.0125). The detection rates of MP in 2013 and 2014 were significantly higher than that in 2012 (P<0.0125). CP had the highest detection rate in 2013, and LP had the highest detection rate in 2014 (P<0.0125). These three pathogens were detected all around the year, and MP had the highest detection rate in all seasons (P<0.0125). The detection rate of mixed infection with three pathogens was 4.35%, and mixed infection with MP and CP was the most common (P<0.0071). Among the children in different age groups, the patients aged 5-16 years showed the highest overall detection rate of three pathogens (P<0.0071). Among the children with different types of ARTI, the children with bronchopneumonia showed the highest overall detection rate of three pathogens (P<0.0045). Conclusions MP, CP, and LP, particularly MP, are important pathogens for children with ARTI in the local area. LP infection tends to increase year by year and should be taken seriously in clinical practice.关键词
急性呼吸道感染/肺炎支原体/肺炎衣原体/嗜肺军团菌/儿童Key words
Acute respiratory tract infection/Mycoplasma pneumoniae/Chlamydia pneumoniae/Legionella pneumophila/Child引用本文复制引用
廖嘉仪,张涛..13 198例急性呼吸道感染住院患儿肺炎支原体、肺炎衣原体及嗜肺军团菌分布特点分析[J].中国当代儿科杂志,2016,18(7):607-613,7.基金项目
广东省医学科研基金（B2014351）；广州市越秀区科技计划项目（2012-WS-002）。 （）
