中国动脉硬化杂志2016，Vol.24Issue(7)：649-656,8.
动脉粥样硬化易损斑块的动物模型和检测技术
Animal Models and Detection Technologies of Vulnerable Atherosclerotic Plaques
陈文强 1张运1
作者信息
- 1. 山东大学齐鲁医院,山东省济南市250012
- 折叠
摘要
Abstract
Vulnerable atherosclerotic plaque rupture leading to thrombosis is the major cause of acute coronary syndromes.While early detection or prevention the vulnerable plaque would be the only way to reduce the risk of this catastrophic life-threatening event,there is frustratingly little progress in either.Lack of suitable animal models has considerably hampered the research progress in understanding the mechanisms occurring in the development of plaque rupture.This review summarizes the currently available vulnerable plaque animal models and invasive and noninvasive imaging modalities used to detect vulnerable plaques,including high frequency duplex ultrasound,coronary tomographic angiography (CTA),magnetic resonance imaging (MRI),intravascular ultrasound (IVUS),optical coherence tomography (OCT),intravascular ultrasound elastography,and inflammatory markers.关键词
动脉粥样硬化/易损斑块/动物模型/影像学/炎症Key words
Atherosclerosis/Vulnerable Plaque/Animal Model/Imaging/Inflammation分类
医药卫生引用本文复制引用
陈文强,张运..动脉粥样硬化易损斑块的动物模型和检测技术[J].中国动脉硬化杂志,2016,24(7):649-656,8.
