中国动脉硬化杂志2016,Vol.24Issue(7):679-682,4.
糖尿病对经皮冠状动脉介入治疗患者长期预后的影响
The Influence of Diabetes on Long-term Prognosis in Patients Treated by Primary Percutaneous Coronary Intervention
摘要
Abstract
Aim To investigate the influence of diabetes on the long-term prognosis in patients with coronary heart disease (CHD) treated by percutaneous coronary intervention (PCI).Methods A total of 2367 consecutive patients with CHD treated by PCI were selected.According to whether there was diabetes,the patients were divided into two groups:diabetes group (n =719) and non-diabetes group (n =1648).The influence of diabetes on the long-term prognosis of patients with CHD after PCI was studied by the COX regression analysis.Results Compared with the non-diabetes group,the rate of male patients and level of high density lipoprotein cholesterol (HDLC) were lower,the levels of triglyceride and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were higher,the proportions of old myocardial infarction (OMI),cardiac dysfunction,hypertension,renal dysfunction and cerebral apoplexy were higher in the diabetes group.The proportion of coronary three-vessel lesion,chronic occlusion ratio and Gensini score were higher,average number of stents was more and the average length of stent was longer in the diabetes group.Postoperative follow-up showed that there was no significant difference on all-cause mortality,major adverse cardiovascular event (MACE),cardiac death,nonfatal myocardial infarction and unplanned repeat revascularization between the two groups.Multivariate COX regression analysis showed that there was no significant correlation between diabetes and long-term prognosis of patients with PCI.Conclusions PCI patients with diabetes have special clinical characteristics,but the long-term prognosis is not significantly adverse.关键词
冠心病/糖尿病/经皮冠状动脉介入治疗/预后Key words
Coronary Heart Disease/Diabetes/Percutaneous Coronary Intervention/Prognosis分类
医药卫生引用本文复制引用
王卓,于彤彤,董媛媛,宋娇磊,李影,陈子涵,王传合,韩苏,孙志军..糖尿病对经皮冠状动脉介入治疗患者长期预后的影响[J].中国动脉硬化杂志,2016,24(7):679-682,4.基金项目
辽宁省科技厅社会发展攻关计划(2011225020) (2011225020)