中国动脉硬化杂志2016，Vol.24Issue(7)：698-700,704,4.
急性心肌梗死患者血清骨膜蛋白水平与疾病预后的关系
Relationship Between Serum Level of Periostin and Prognosis of Patients with Acute Myocardial Infarction
摘要
Abstract
Aim To investigate the relationship between serum level of periostin and prognosis of patients with acute myocardial infarction (AMI).Methods Serum periostin was measured by using enzyme-linked immunosorbent assay in 178 patients with AM1 immediately after hospitalization.All patients were followed up for 12 and 18 months.Major adverse cardiac and cerebrovascular events (MACCE) were counted,including death,stroke/transient ischemic attack,recurrent chest pain,ischemia and re-admission.The relationship between the level of periostin and the prognosis of cardiovascular disease was evaluated.Results Follow-up results showed that MACCE composite end-point in high periostin group of AMI patients was higher than that in low periostin group after 12 months follow-up (P＜0.05).Recurrent chest pain,ischemia and re-admission,and MACCE composite end-point in high periostin group were higher than those in low periostin group after 18 months follow-up (P＜0.05).The results suggested that the serum level of the periostin might be used as an index to predict the prognosis of patients with myocardial infarction.Conclusion The serum level of periostin may be related to the prognosis of cardiovascular disease in patients with AMI.关键词
急性心肌梗死/骨膜蛋白/预后Key words
Acute Myocardial Infarction/Periostin/Prognosis分类
医药卫生引用本文复制引用
凌琳,承燕,顾少华..急性心肌梗死患者血清骨膜蛋白水平与疾病预后的关系[J].中国动脉硬化杂志,2016,24(7):698-700,704,4.基金项目
江苏省自然科学基金青年基金项目(BK20140296) （BK20140296）
苏州市科教兴卫项目(KJXW2013004) （KJXW2013004）
苏州大学校级青年教师自然科学基金项目(SDY2013A29) （SDY2013A29）
