中国动脉硬化杂志2016，Vol.24Issue(7)：753-756,4.
C肽与动脉粥样硬化的研究进展
Research Progress on C-peptide and Atherosclerosis
摘要
Abstract
The patients with metabolic syndrome or type 2 diabetes mellitus are characterized by insulin resistance and have more risks to develop extensive atherosclerosis,even it occurs before hyperglycemia.Atherosclerosis is the leadng cause of death in diabetic population.Thus it is important to explore the mechanisms of atherosclerosis.Besides the traditional risk factors,C-peptide which is considered no biological activity may play role in atherogenesis.It involves inflammation of artery and results in monocyte/macrophage accumulation as well as smooth muscle cell proliferation.Several cohort studies suggest that increased C-peptide levels relate to all-cause death,cardiovascular disease and cancer mortality.This review focuses on the new biological functions of C-peptide based on in vitro,vivo research and clinical studies.关键词
C肽/动脉粥样硬化/胰岛素抵抗/心血管疾病Key words
C-peptide/Atherosclerosis/Insulin Resistance/Cardiovascular Disease分类
医药卫生引用本文复制引用
刘谦..C肽与动脉粥样硬化的研究进展[J].中国动脉硬化杂志,2016,24(7):753-756,4.基金项目
北京市保健科研课题(京13-09号)资助 （京13-09号）
