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代谢综合征对颈动脉内中膜厚度影响的性别差异研究

龚莉 葛莎莎 张建国 章秋

中国全科医学2016,Vol.19Issue(20):2395-2398,4.
中国全科医学2016,Vol.19Issue(20):2395-2398,4.DOI:10.3969/j.issn.1007-9572.2016.20.007

代谢综合征对颈动脉内中膜厚度影响的性别差异研究

Difference of the Influence of Metablic Syndrome on Carotid Intima-media Thickness Between Different Gender

龚莉 1葛莎莎 2张建国 3章秋3

作者信息

  • 1. 230001 安徽省合肥市,安徽医科大学第一附属医院内分泌科
  • 2. 皖北煤电集团总医院内分泌科
  • 3. 皖北煤电集团总医院体检中心
  • 折叠

摘要

Abstract

Objective To investigate the difference of the influence of metabolic syndrome(MS)on carotid intima -media thickness(CIMT)between two genders. Methods We enrolled 593 people who received physical examination in the General Hospital of Wanbei Coal Group from October 8,2013 to February 25,2014. After fasting for 8 to 12 hours,the subjects received conventional physical examination and biochemical criterion detection. Two professional physicians who had been trained measured CIMT by short axis,and average value was calculated. Results The MS prevalence was 29. 8% (105 / 353) for males and 24. 6% (59 / 240)for females,without significant difference between them(χ2 = 1. 087,P > 0. 05). Among males and females before and after menopause,subjects with different number of MS components were significantly different in CIMT (F = 12. 240,8. 850,9. 510;P < 0. 001). When having no component or one component,males and females before and after menopause were significantly different in CIMT( F = 8. 890,8. 620;P < 0. 001);males and females after menopause were higher than females before menopause in CIMT(P < 0. 05). When having ≥3 components,males and females after menopause were significantly different in CIMT( F = 0. 670,P = 0. 002);males and females after menopause were higher than females before menopause in CIMT,and females after menopause was higher than males in CIMT( P < 0. 05). Logistic regression analysis showed that the MS was a risk factor for the increase in CIMT thickness of female〔 OR = 5. 611,95% CI(1. 398, 22. 632),P < 0. 05〕,while no correlation was found between the MS and the increase in CIMT thickness of males〔 OR =1. 091,95% CI(0. 906,1. 314),P > 0. 05〕. Conclusion Difference exists in the influence of MS on CIMT between different genders,and MS has more significant influence on CIMT in females.

关键词

代谢综合征/颈动脉内中膜厚度/性别

Key words

Metabolic syndrome/Carotid intima - media thickness/Gender

分类

医药卫生

引用本文复制引用

龚莉,葛莎莎,张建国,章秋..代谢综合征对颈动脉内中膜厚度影响的性别差异研究[J].中国全科医学,2016,19(20):2395-2398,4.

中国全科医学

OA北大核心CSTPCD

1007-9572

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