摘要
Abstract
Objective To investigate the difference of the influence of metabolic syndrome(MS)on carotid intima -media thickness(CIMT)between two genders. Methods We enrolled 593 people who received physical examination in the General Hospital of Wanbei Coal Group from October 8,2013 to February 25,2014. After fasting for 8 to 12 hours,the subjects received conventional physical examination and biochemical criterion detection. Two professional physicians who had been trained measured CIMT by short axis,and average value was calculated. Results The MS prevalence was 29. 8% (105 / 353) for males and 24. 6% (59 / 240)for females,without significant difference between them(χ2 = 1. 087,P > 0. 05). Among males and females before and after menopause,subjects with different number of MS components were significantly different in CIMT (F = 12. 240,8. 850,9. 510;P < 0. 001). When having no component or one component,males and females before and after menopause were significantly different in CIMT( F = 8. 890,8. 620;P < 0. 001);males and females after menopause were higher than females before menopause in CIMT(P < 0. 05). When having ≥3 components,males and females after menopause were significantly different in CIMT( F = 0. 670,P = 0. 002);males and females after menopause were higher than females before menopause in CIMT,and females after menopause was higher than males in CIMT( P < 0. 05). Logistic regression analysis showed that the MS was a risk factor for the increase in CIMT thickness of female〔 OR = 5. 611,95% CI(1. 398, 22. 632),P < 0. 05〕,while no correlation was found between the MS and the increase in CIMT thickness of males〔 OR =1. 091,95% CI(0. 906,1. 314),P > 0. 05〕. Conclusion Difference exists in the influence of MS on CIMT between different genders,and MS has more significant influence on CIMT in females.关键词
代谢综合征/颈动脉内中膜厚度/性别Key words
Metabolic syndrome/Carotid intima - media thickness/Gender分类
医药卫生