中国全科医学2016，Vol.19Issue(20)：2416-2418,2419,4.DOI:10.3969/j.issn.1007-9572.2016.20.011
术前及术后贫血对肺大细胞神经内分泌癌患者预后的影响
Impact of Preoperative and Postoperative Anemia on the Prognosis of Pulmonary Large Cell Neuroendocrine Carcinoma Patients
王岩 1周军 2戴素丽 3许西娥 1陶仁海 4刘俊峰1
作者信息
- 1. 050011 河北省石家庄市，河北医科大学第四医院胸外科
- 2. 定州市武警 8640部队医院
- 3. 河北省肿瘤研究所
- 4. 050011 河北省石家庄市，河北医科大学第四医院手术室
- 折叠
摘要
Abstract
Objective To explore the influence of preoperative and postoperative anemia on the prognosis of patients with pulmonary large cell neuroendocrine carcinoma( LCNEC). Methods From July 2007 to July 2013,we enrolled 44 LCNEC patients who received treatment in the Department of Thoracic Surgery of the Fourth Hospital of Hebei Medical University. Data of clinical features of the patients were collected. With the date of surgery as the start point and death as the endpoint,survival time of patients was calculated. The follow - up was conducted until August 2014. Results There were significant differences in survival time among patients with different genders,ages,history of smoking,diameters of tumor, pathological types,TNM stages,surgical methods and between patients with and without preoperative and postoperative anemia, lymph node metastasis(P < 0. 05). Cox proportional hazard regression model analysis showed that age〔HR = 6. 751,95% CI (3. 576,15. 438)〕,history of smoking〔 HR = 3. 438,95% CI( 1. 053,6. 538 )〕,pathological types〔 HR = 10. 643, 95% CI(6. 634,21. 982)〕,preoperative anemia〔 HR = 0. 043,95% CI(0. 027,0. 051)〕,postoperative anemia〔 HR= 8. 451,95% CI(4. 885,9. 372)〕and surgical methods〔 HR = 2. 334,95% CI(1. 658,21. 575)〕were influencing factors for the prognosis of LCNEC patients(P < 0. 05). Conclusion Preoperative and postoperative anemia are related with the prognosis of LCNEC patients.关键词
癌,非小细胞肺/贫血/预后Key words
Carcinoma,non - small - cell lung/Anemia/Prognosis分类
医药卫生引用本文复制引用
王岩,周军,戴素丽,许西娥,陶仁海,刘俊峰..术前及术后贫血对肺大细胞神经内分泌癌患者预后的影响[J].中国全科医学,2016,19(20):2416-2418,2419,4.
